Lifestyle interventions for severe mental illness: time to deliver

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We have the evidence that lifestyle interventions work. Now what? The third Lancet Psychiatry Commission focuses on the messy business of implementation.

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Is it a gut feeling? How the microbiome may shape perinatal mental health in women with higher body weight

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What if perinatal mental health started in the gut? New research from Finland suggests certain bacteria may be associated with depressive and anxiety symptoms during pregnancy and after birth, raising questions about inflammation, causality, and the future of microbiome-based screening and treatment.

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Feeding the mind: early signs that keto could help with bipolar disorder

Emerging research into the effects of a ketogenic diet have reported neuroprotective and anti-inflammatory mechanisms along with a positive metabolic effect

This pilot study explored how a ketogenic diet affects mood, metabolic health, and brain chemistry in people with bipolar disorder. The results are early, but they offer food for thought.

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Probiotics for bipolar disorder and schizophrenia

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Mary Butler explores a recent randomised controlled trial of probiotic formulations for patients with bipolar disorder or schizophrenia spectrum disorder.

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The role of the gut microbiome in treatment-resistant schizophrenia

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Nuala Murray explores a recent Australian case-control study that looks at the associations between changes in gut microbiota and schizophrenia diagnosis, treatment resistance, and clozapine response.

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The impact of calorie labelling on menus for individuals with eating disorders

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Lucy Hyam discusses a qualitative study that explored the impact of calorie labelling on menus for individuals with current or past experience of eating disorders.

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Gut microbiome disruptions in depression: shifting the focus to metabolic signatures in blood

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Gerard Clarke explores a recent study which looks into the interplay of metabolome and gut microbiome in individuals with major depressive disorder.

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South Asia’s silent struggle: people with severe mental illness suffer high burden of physical illness

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An international group of experts from the University of York CADA Implementation Science Summer School summarise a recent study on the prevalence of physical health conditions and health risk behaviours in people with severe mental illness in South Asia (Bangladesh, India and Pakistan).

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Does what you eat affect how you feel?

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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

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Critiquing the evidence behind the “evidence-based conclusions” about ADHD

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Shuichi Suetani and Gaj Panagoda explore the World Federation of ADHD International Consensus Statement published in 2021, which contains “208 evidence-based conclusions about attention-deficit hyperactivity disorder.

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