This review of regenerative endodontic treatment included 14 small observational studies of limited quality suggesting a possible influence of apical diameter on clinical outcomes.
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17 studies, none of which were at low risk of bias, were included in this review of the effect of type of instrumentation on post endodontic pain. The findings suggest lower incidence and intensity of postoperative pain with rotary instruments compared to hand files.
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This review of dexamethasone for controlling pain following endodontic treatment included 5 relatively small RCTs . The findings suggest statistically significant reduction of pain in patients receiving dexamethasone at 8,12, and 24 hours.
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This review of the efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) as premedication on the success of inferior alveolar nerve block includes 13 RCTs suggesting NSAIDs have a positive impact on success.
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This review of the efficacy of corticosteroids on postoperative endodontic pain. found that patients receiving corticosteroids reported significantly lower pain scores at 6, 12 and 24hrs postoperatively.
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This review of dental pulp test accuracy included 28 studies. While the findings suggest that laser doppler flowmetry and pulse oximitery are the most accurate the quality of the available studies is low.
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This network meta-analysis of oral premedication to improve anaesthetic success of inferior alveolar nerve block in patients with irreversible pulpitis suggest that that oral premedication with dexamethasone, NSAIDs and Tramadol increases the success rate.
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19 studies were included in this review of core-carrier obturation techniques in endodontic treatment. Success rates was 83%(95CI; 69-91%) with 24% suffering postoperative pain and 31% having overfilling.
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This review of regenerative endodontic treatment (RET) or mineral trioxide aggregate (MTA) apical plug (MAP)in the treatment of teeth with pulp necrosis and open apices used broad inclusion criteria. 144 studies were identified suggesting promising outcomes. However the quality of the available evidence is very low and more high quality research is needed.
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This review of regenerative endodontics for non-vital immature permanent teeth included 14 studies. Although suggesting good outcomes overall they were of low quality with a high risk of bias. Larger high quality studies are needed.
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