Genetics of depression: risk factors and protective factors

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Marcus Munafò reports on a new genome-wide association study that identifies 44 risk variants and helps us to further refine the genetic architecture of major depressive disorder.

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Nicotine reverses hypofrontality in animal models of addiction and schizophrenia

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Marcus Munafo looks at a complex and sophisticated series of experiments that provide further insight into the relationships between genetic risk, cigarette smoking and schizophrenia.

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#MQScienceMeeting: transforming lives with better mental health research

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André Tomlin looks back at the #MQScienceMeeting Mental Health Science Meeting that took place in London on 2-3 Feb 2017.

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Chronic pain and depression: genetic and environmental risks

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Marcus Munafo explores a recent study that uses genetic data and family environmental information to quantify the risk of chronic pain and the contribution of risk variants for major depressive disorder.

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How can genetics help us better understand, diagnose and treat mental illness? An interview with Andrew McIntosh

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This World Mental Health Day, we share a Wellcome Trust interview with Professor Andrew McIntosh, who has a £4.7 million award to explore why people develop depression. He tells Wellcome how he hopes his work will improve the lives of people with mental health conditions, and how he looks after his own mental wellbeing.

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Schizophrenia and urban deprivation: When the facts change, I change my mind. What do you do?

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Samei Huda reviews a recent study of schizophrenia and subsequent urban deprivation, which revisits the social drift hypothesis.

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Psychiatric disorders: what’s the significance of non-random mating?

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Marcus Munafo considers the implications of a recent Swedish population study, which explores patterns of non-random mating within and across 11 major psychiatric disorders.

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Eating disorders and suicide

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David Steele considers the implications of a Swedish population registry study, which finds that people with eating disorders and their close relations are at increased risk for attempting and/or completing suicide.

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