The optimal state of the mouth and normal functioning of the organs of the mouth without evidence of disease.
Obstructive sleep apnoea–Effectiveness of different mandibular advancement devices

This review of the the effectiveness of different mandibular advancement devices for obstructive sleep apnoea included 50 RCTS. While the findins suggest that mono-bloc MADs are more effective duo-bloc devices the quality of the available evidence is very low.
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