psychosis

Psychosis is a condition that affects a person’s mind and causes changes to the way that they think, feel and behave. A person who experiences psychosis may be unable to distinguish between reality and their imagination. People who are experiencing psychosis are sometimes referred to as psychotic. They may have hallucinations (where you see or hear things that are not there) and/or delusions (where you believe things that are untrue).

Our psychosis Blogs

Trauma-focused therapy for psychosis: helpful for delusions, less so for hallucinations

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A new meta-analysis from Toutountzidis and colleagues finds trauma-focused therapies meaningfully reduce delusions in psychosis, but offer limited benefit for hallucinations. Younger people gain most.

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Lifestyle interventions for severe mental illness: time to deliver

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We have the evidence that lifestyle interventions work. Now what? The third Lancet Psychiatry Commission focuses on the messy business of implementation.

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A stitch in time: early intervention for young people – promising but patchy evidence

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Two major reviews find early intervention shows promise for youth mental health, but the evidence is stronger for psychosis than for anxiety and depression.

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Can we predict and prevent weight gain in early psychosis?

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New research suggests that weight gained in the first 12 weeks of antipsychotic treatment is the biggest driver of long-term obesity in psychosis.

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Stop, reduce or stay on antipsychotics after first-episode psychosis?

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Once symptoms stabilise after a first episode of psychosis, should medication continue? A four-year RCT explores the risks and rewards of dose reduction.

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Spotting bipolar and psychosis risk earlier using routine clinical records

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A 28-predictor model using routine mental health records correctly identified risk for psychotic or bipolar disorders around 80% of the time, outperforming existing assessment tools in a study of 127,000 people.

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Shared genetic patterns found across 14 psychiatric disorders

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Psychiatric disorders share genetic variants that cluster into five main factors. Understanding shared biology could improve treatment, but more diverse genetic data urgently needed.

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Measuring paranoid beliefs: can adaptive testing support routine clinical care?

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Simulation study suggests computerised adaptive testing could reduce paranoia assessment from 10 items to 4 while maintaining accuracy. Real-world implementation and clinical testing needed.

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Resistance training in psychiatric rehab settings is feasible and safe for psychosis

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Feasibility trial found resistance training was safe and acceptable for people with psychosis in psychiatric rehabilitation wards, challenging assumptions about patient capabilities and safety.

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Do antipsychotics slow down thinking? New evidence from healthy volunteers

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New research reveals how antipsychotic medications affect working memory speed in healthy adults, providing crucial insights into the cognitive side effects of these widely prescribed drugs.

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