Results: 127

For: oral medicine and pathology

Systemic Lupus Erythematosus: What are the orofacial manifestations and dental considerations?

Lupus (SLE)

Marianne Dobson takes a look at this systematic review of the orofacial manifestations of systemic lupus erythematosus (SLE). The review included 30 studies and provides a narrative summary of a issues related to orofacial symptoms and management. However good quality prospective studies are needed to improve the the quality of evidence surrounding this topic.

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Oral Proliferative Verrucous Leukoplakia: What are the clinical features?

Leukoplakia , Verrucous

Marianne Dobson in her first blog for the Dental Elf takes a look at a systematic review looking at the main clinical features of proliferative verrucous leukoplakia

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Oral lichen planus: How common is it worldwide?

Lichen Planus -histopathology

This review of the global prevalence of oral lichen planus (OLP) included 66 observational studies providing an estimate of prevalence of 1.01% (0.74 to 1.32%).

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Mouthwash; can it reduce levels of Covid-19 in the mouth?

shutterstock_12720943-mouthwash

This latest rapid review from Mark-Steven Howe looks at the virucidal efficacy of commonly used oral mouthwashes. No high quality evidence was identified. Some demonstrate good virucidal properties but have poor substativity with the benefits being lost within a few minutes.

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Oral submucous fibrosis: Is treatment with hyaluronidase and corticosteroids effective?

A_close_up_of_Areca_nut

This review of the efficacy of hyaluronidase combined with corticosteroids in the management of oral submucous fibrosis (OSF)included 6 small RCTs of short duration. Only one of the RCTs was considered to be at low risk of bias so additional well conducted and reported studies with larger sample are needed to evaluate treatments for OSF.

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Botulinum toxin for management of temporomandibular disorders

shutterstock_128569418

This review of botulinum toxin (BTX) in the management of temporomandibular joint disorders (TMD) included 7 small RCTs of low quality. high quality well reported RCTs with larger sample sizes and longer follow times are needed to properly assess the effectiveness of BTX in the management of TMD.

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Antifungal drugs for oral candidiasis

Candida Albicans

This network meta-analysis of the efficacy of antifungal drugs on oral candidiasis included 31 RCTs of overal low quality suggesting that fluconazole may be the most effective.

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Oral leukoplakia: Malignant transformation rate

OLYMPUS DIGITAL CAMERA

This review of the rate of malignant transformation of oral leukoplakia included 34 many retrospective observational studies. The estimated mean malignant transformation rate was 9.7% (95%CI; 7.8% to 11.7%).

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Oral candidiasis: Are probiotics effective?

Candida albicans

This review of the the efficacy of probiotics on oral Candida spp. includes 12 RCTs and suggests a possible benefit. However the quality of the evidence is limited so the findings should be intepreted cautiously.

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Oral lichen planus: malignant transformation rate

Lichen_planusWickham's

This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of 0.44%.

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