This review to evaluate the effect of low-level laser therapy (LLLT) on burning pain, quality of life, and negative emotions in patients with burning mouth syndrome included 14 RCTs only two of which were at low risk of bias.While the findinds suggest that LLLT has a positive effect the quality of evidence means the findings should be interpreted cautiously.
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This review of different topical medications for the management of recurrent aphthous stomatitis (RAS) included 43 RCTs. No significant differences were found for any if the treatments assessed and a majority of the included RCTs (76%) were considered to be at high risk of bias.
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This umbrella review of the proportion of oral cancer development in oral submucous fibrosis patients included 4 systematic reviews published between 2019 and 2022. Mean values for malignant transformation across the reviews range from 4.2% to 6%.
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This review of the prevalence of oral leukoplakia reported from 1996 to 2022,by continent, definition, age, and living habits included 69 studies. The findings provided a global pooled estimate for prevalence of 3.41% (95%CI: 2.65 to 4.26%).
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This review of the rate of malignant transformation (MT) of oral leukoplakia and potential risk factors included 26 mainly retrospective studies. The findings indicate a MT of 7.2% (95%CI; 5.40 to 9.10%) similar to those of another recent review whihc estimated MT as 9.8% (95%CI; 7.9 to 11.7%).
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This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.
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This review and network meta-analysis (NMA) of pharmacological treatments for the management of pain subsequent to simple and surgical tooth extraction included 85 RCTs. There was moderate- and high-certainty evidence that for surgical dental extractions that ibuprofen 200 to 400 mg plus acetaminophen 500 to 1,000 mg was the most effective for pain relief.
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This eview of the effectiveness of effervescent tablets in the cleaning and sanitising of removable prostheses included 23 RCTs. Six RCTs contributed to meta-analyses which indicate that use of brushing and effervescent tables reduce biofilm and bacterial conts more than brushing alone.
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This review of the comparative efficacy of interventions used for the treatment of denture stomatitis(DS) included 35 RCTs with 25 studies contributing to the meta-analyses. The findings suggest that topical antifungal agents produced the most effective clinical improvement and microwave disinfection and topical antifungals the best mycological resolution. Only one of the RCTs was at low risk of bias so the findings should be interpreted cautiously.
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This review of the efficacy of probiotics in reducing halitosis of dental origin, when compared to a placebo intervention included 8 RCTs. Only one of the study was considered to be at low risk of bias with the authos assessing the evidence as not suggestive of a convincing benefit for the use of probiotics for treatment outcomes of halitosis.
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