Results: 97

For: oral medicine and pathology

Sjögren’s syndrome: treatments for dry mouth and hyposalivation

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36 studies were included in this review of treatment options for xerostomia, hyposalivation and quality of life in patients with Sjögren’s syndrome provinding evidence to support pilocarpine use. However the number of studies were limited and adverse effects were common.

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Geographic tongue: little evidence for the management of symptomatic cases

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This review of treatments for the management of symptomatic benign migratory glossitis (BMG) only included 11 small low quality studies providing little evidence for the management of symptomatic BMG.

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Oral lichen planus: Rate of malignant transformation

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This review of the malignant transformation rate (TR) of oral lichen planus included 21 observational studies the majority of which were retrospective. The overall estimate of TR was 1.4%.

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Oral potentially malignant disorders – how common are they?

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This review of the prevalence of oral potentially malignant disorders included 22 observational studies providing a pooled estimate for prevalence of 4.47% (95% CI;2.43-7.08).

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Denture stomatitis: Is there a role for low-level laser therapy?

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This review of low-level laser therapy (LLLT) or photodynamic therapy (PDT) in the treatment of denture stomatitis only identified 4 small RCTs providing limited low quality evidence of clinical effectiveness.

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Dentine hypersensitivity: Effectiveness of desensitising toothpastes

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This review evaluating the effectiveness of desensitising toothpastes included 53 RCTs. Most agents with the exception of those containing strontium or amorphous calcium phosphate were effective in relieving dentine hypersensitivity compared with negative controls.

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Local anaesthetics for preventing pain during dental treatment

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123 RCTs were included in this Cochrane review of local anaesthetic agents for preventing pain during dental treatment. 14 types of local anaesthetic were included evidence to support the use of one over another was limited so further research is needed to clarify the effectiveness and safety of one local anaesthetic over another.

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Corticosteroids for post-endodontic pain

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This review of the efficacy of corticosteroids on postoperative endodontic pain. found that patients receiving corticosteroids reported significantly lower pain scores at 6, 12 and 24hrs postoperatively.

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Keratocysts: conservative treatment approaches?

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29 mainly retrospective studies were included in this review of conservative management approaches for odontogenic keratocysts. While the findings suggest use of decompression followed by enucleation data for recurrence were lower than those found in previous reviews of the topic. High quality prospective studies are needed.

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Buffering local anaesthetics to reduce dental injection pain?

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14 RCTs were included in this review of the effect of buffering local anaesthetics in reducing infiltration pain and anaesthesia onset time in dentistry. While slight reductions in onset time was seen in inflamed tissues and for IAN block these were not considered to be clinically significant. However the overall quality of the evidence was low.

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