Results: 184

For: oral medicine and pathology

Additives to lidocaine and the success of the inferior alveolar nerve block

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This review of the effect of additives incorporated into lidocaine solution on the success of inferior alveolar nerve block (IANB) included 12 RCTs. The findings suggest that additives did not improve the success rate of IANB but the evidence is of low to very low certainty.

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Antibiotics to prevent bacterial endocarditis following dental procedures

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This Cochrane review update of antibiotic prophylaxis before invasive dental procedures in people at risk or at high risk of bacterial endocarditis included one case-controlled study. Consequently, there is no clear evidence about whether antibiotic prophylaxis is effective or ineffective against bacterial endocarditis in at-risk people who are about to undergo an invasive dental procedure.

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Photodynamic therapy for denture stomatitis

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This review of comparing photodynamic therapy (PDT) and antifungals or the treatment of denture stomatitis included 5 studies involving a total of 218 patients. While the findings suggest that PDT is effective none of the the studies was at low risk of bias and the treatment protocols investigated differ.

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Ibuprofen prior to lower third molar removal

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This review of the effect of pre-emptive ibuprofen on post-operative pain after lower third molar surgery included 5 RCTs. Only one of the included studies was at low risk of bias so there is insufficient evidence to support the routine use of pre-emptive ibuprofen to reduce post-operative pain after lower third molar removal

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Management of dental patients taking anticoagulants or antiplatelet drugs

SDCEP- Anticoag-platelets 2022

We take a look at the recently updated guidance on the Management of Dental Patients Taking Anticoagulants or Antiplatelet Drug from the Scottish Dental Clinical effectiveness programme (SDCEP).

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Oral lichen planus and autoimmune disorders

Lichen_planusWickham's

This review of the prevalence of autoimmune disorders in patients with oral lichen planus (OLP) and their magnitude of association included 153 studies. while links between autoimmune thyroid diseases and diabetes mellitus where shown a majority of the included studies were of low quality.

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Medication‐related osteonecrosis of the jaw and non-antiresorptive medications

osteonecrosis

This review of the association between non-antiresorptive medications and medication‐related osteonecrosis of the jaw (MRONJ) included 70 studies. A majority of the studies (77%) were case series and the quantity and quality of the evidence is low so the findings should be interpreted cautiously.

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Malic acid spray for treating xerostomia

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This review of the efficacy of topical sialogogue spray containing malic acid 1% for treating xerostomia included 5 RCTs involving 244 patients. While the findings suggested a benefit the available studies are small, of short duration and none are at low risk of bias.

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Early detection of oral cancer and oral potentially malignant disorders

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This Cochrane review update of the diagnostic test accuracy of conventional oral examination, vital rinsing, light-based detection, mouth self-examination, remote screening, and biomarkers, used singly or in combination, for the early detection of OPMD or OSCC in apparently healthy adults included 18 studies.

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Oral lichen planus and malignant transformation

Lichen_planus

This review of high quality studies of oral lichen planus malignant transformation rate included 10 observational studies. The findings found a higher level of malignant transformation in higher quality studies 2.28% (95%CI; 1.49 to 3.20) compared with reviews including lower quality studies 1.14% (0.84 to 1.49).

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