The Goldilocks zone: getting ADHD medication ‘just right’

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What psychostimulant dose is ‘just right’ for people with ADHD? This blog explores the first dose-effect network meta-analysis across age groups, unpacking what it means for clinicians navigating the fine line between therapeutic inertia and unnecessary dose escalation.

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Autism and restrictive eating disorders: a battle of the senses

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Around 30% of people with anorexia may screen positive for autism, yet treatment models rarely reflect this. A new qualitative review asks what autistic people actually need from eating disorder services.

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Childhood spent behind bars: the impact of immigration detention centres on children’s mental health

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A new systematic review pools data from 9,620 detained children across 8 countries and finds alarming rates of depression, PTSD and self-harm. The harm rises the longer and harsher the detention, and no form of it is safe.

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What works in domestic abuse and sexual violence services? Encouraging signals, fragmented evidence, and an urgent measurement problem

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Services for domestic abuse and sexual violence are widely delivered and highly valued, but how confident can we be that they work? A new UK-focused systematic review of what the evidence actually shows.

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When staff wellbeing programmes backfire: lessons from a systematic review of mental health ward interventions

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Around 40% of mental health professionals experience emotional exhaustion, but do the interventions designed to help them actually work? A new review suggests the answer is more complicated than most ward managers would like.

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Can experiencing mental illness literally cause heartache?

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A systematic review of 22 million people finds several mental health conditions, including PTSD, depression and anxiety, are linked to higher acute coronary syndrome risk.

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Brief interventions after suicide attempts: does connection save lives?

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Fifty years after Jerome Motto’s caring letters, this meta-analysis suggests brief interventions can help people through the high-risk period after a suicide attempt. However, we still don’t know how they work.

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CBT for depression in primary care: gold standard, or one option among many?

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Does CBT really outperform other treatments for depression in primary care settings? A recent systematic review suggests patients may have more options than we think.

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Trauma-focused therapy for psychosis: helpful for delusions, less so for hallucinations

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A new meta-analysis from Toutountzidis and colleagues finds trauma-focused therapies meaningfully reduce delusions in psychosis, but offer limited benefit for hallucinations. Younger people gain most.

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A stitch in time: early intervention for young people – promising but patchy evidence

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Two major reviews find early intervention shows promise for youth mental health, but the evidence is stronger for psychosis than for anxiety and depression.

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