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Antidepressants and psychotherapy for adolescent depression: can they be compared? #ActiveIngredientsMH

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Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.

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Periodontitis: Systemic antimicrobials as an adjunct to non-surgical treatment

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This Cochrane review of the effects of systemic antimicrobials as an adjunct to scaling and root planing (SRP) for the non-surgical treatment of patients with periodontitis identified 45 RCTs. However the evidence is of very low certainty to inform tclinicians and patients if adjunctive antibiotics are beneficial.

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Effects of NSAIDs on dental implant osseointegration

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In his first blog for the Dental Elf Alex Orchard looks at a review of studies assessing the impact of non-steroidal antiflamatory drugs (NDAIDs) on dental implant osseointegration. Only a very small number of studies were identified providing insufficient information to draw any conclusions.

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Staff views on the impact of the COVID-19 pandemic on mental health services and service users #COVIDMentalHealth

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Charlotte Huggett reviews a recent mixed-methods study from the Mental Health Policy Research Unit, which explores mental health staff views on the impact of the COVID-19 pandemic on mental health patients and services.

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Dental bleaching in-office: What concentration of hydrogen peroxide?

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This review of difference concentrations of hydrogen peroxide for in-office dental bleaching on colour change and bleaching sensitivity included 25 RCTs. The findings indicate that low and medium hydrogen peroxide concentrations had lower risk and intensity of bleaching sensitivity and no difference in colour change efficacy compared with high concentrations.

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Increased suicide risk where race/ethnicity and sexual orientation intersect

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In his debut blog, Brendan Dunlop summarises a study finding a relationship between minority sexual orientation, ethnicity and suicide risk in adolescents.

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MDMA-assisted psychotherapy for PTSD: moving towards post-traumatic growth?

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Aster Daniel summarises a recent study exploring post-traumatic growth after MDMA-assisted psychotherapy for PTSD (post-traumatic stress disorder).

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Digital pathology: Diagnostic concordance and discordance

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Manas Dave considers this review of the safety and reliability of digital pathology. The review included 24 studies showing high concordance between digital pathology and light microscopy suggesting that digital pathology is a viable alternative to light microscopy.

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Denture stomatitis: Is microwave disinfection effective?

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This review of the effectiveness of removable complete denture disinfection using microwaves for the treatment of denture stomatitis included 3 small RCTs. While the findings suggest that microwave may be effective the evidence is of low certainty so additional high quality well reported studies are needed.

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Harm reduction for young people who self-harm: “a double-edged sword”

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Rachel Rowan Olive thinks through a recent qualitative study about young peoples’ perspectives on the role of harm reduction techniques in the management of their self-harm.

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