Sleep bruxism: validity of diagnostic tools

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This review of diagnostic tools for sleep bruxism included 8 studies the majority being at high risk of bias. Portable diagnostic devices had best validity but quality of evidence was very-low to moderate.

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Identifying cultural issues in diagnostic assessment: the Cultural Formulation Interview

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Clarissa Giebel considers the feasibility, acceptability and clinical utility of the Cultural Formulation Interview; a tool designed to remove barriers to effective diagnosis for people from black and minority ethnic groups.

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#MQScienceMeeting: transforming lives with better mental health research

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André Tomlin looks back at the #MQScienceMeeting Mental Health Science Meeting that took place in London on 2-3 Feb 2017.

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How can genetics help us better understand, diagnose and treat mental illness? An interview with Andrew McIntosh

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This World Mental Health Day, we share a Wellcome Trust interview with Professor Andrew McIntosh, who has a £4.7 million award to explore why people develop depression. He tells Wellcome how he hopes his work will improve the lives of people with mental health conditions, and how he looks after his own mental wellbeing.

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Digital imaging for caries: direct digital sensors or photostimulable phosphor plates?

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This review compared direct digital sensors and indirect photostimulable phosphor plates for the detection of caries. Six studies were included in the review with 4 contributing to the meta-analysis. There was no significant difference between the two systems and they displayed good specificity and limited sensitivity.

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Whooley questions have high sensitivity and modest specificity in the detection of depression

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Ian Anderson on a recent diagnostic accuracy meta-analysis, which shows that the Whooley questions for depression are effective at ruling out the condition, but that false positives are common.

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Salivary biomarkers for diagnosing periodontal disease

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This review of salivary biomarkers for diagnosing periodontal disease only identified 4 studies at high risk of bias but suggests a small number of potential biomarkers. However the findings should be interpreted with caution.

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Prognosis of brief psychotic episodes

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Samei Huda presents the findings of a new meta-analysis, which explores the prognostic significance of competing ways of defining and measuring brief psychotic episodes.

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Is it bipolar disorder or borderline personality disorder?

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Murtada Alsaif considers the challenges facing psychiatrists in diagnosing bipolar disorder or borderline personality disorder. He reports on a recent qualitative study that explores the practical experience of psychiatrists and nurses and concludes that clinical diagnostic practice cannot reliably distinguish the two conditions.

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Improving diagnosis of bipolar disorder: can blood-based diagnostic panels help?

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Can blood-based diagnostic panels help us reduce the misdiagnosis and inappropriate treatment often experienced by people with bipolar disorder? Murtada Alsaif reviews a recent retrospective study that has some encouraging findings for biologically identifying the disease.

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