This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.
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This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.
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There is an ongoing debate about the management of patients with oral cavity squamous cell carcinoma and clinically negative cervical lymph nodes. Some clinicians favour preventive elective neck dissection (END) which although is linked with favourable survival has an adverse effect on quality of life while others adopt a wait and watch policy. The aim [read the full story…]
This review of of the effects of oral supplementation on the prevention and/or treatment of oral mucositis in patients with cancer undergoing chemotherapy and/or radiotherapy included 12 RCTs and suggest that Zinc supplements may be beneficial.
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This review of treatments for actinic cheilitis included 29 mainly observational studies providing little evidence to identify the best treatment approaches.
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This review of the association between coffee intake and the risk of oral cancer includes 19 studies and suggestes that higher intak may be linked with a reduced risk of oral cancer.
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This review of a link between past dental visits/check-ups and the incidence cancers of head and neck includes 38 studies the majority of which are case-controlled studies. The findings suggest that those are irregular of never attenders are more likely to have head and neck cancer.
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This review evaluating the evidence on the effectiveness of curcumin in the management of oral submucous fibrosis included 6 small RCTs providing inconclusive evidence of a potential benefit.
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12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.
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This review of the prevalence of oral potentially malignant disorders included 22 observational studies providing a pooled estimate for prevalence of 4.47% (95% CI;2.43-7.08).
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