Manas Dave looks at a recent review of which considers the efficacy of optical fluorescence imaging as an adjunct to clinical oral examination for the detection of oral mucosal lesions. The review includes 27 studies and provides evidence to support additional high quality studies to assess its effectiveness.
[read the full story...]
Manas Dave takes a look at this review evaluating the prophylactic and therapeutic effects of low-level laser therapy (LLLT) in patients who might or have developed oral mucositis during chemotherapy or radiotherapy.
[read the full story...]
This review assessing the evidence of the impact of replacing missing teeth with dentures on the development of osteoradionecrosis in patients who have radiotherapy for head and neck cancer only identified 3 case-controlled studies of very low quality.
[read the full story...]
This review comparing primary care doctors and dentists in the referral of oral cancer included 22 mainly retrospective studies. Doctors refered sliightly more than dentists, typically 50% compared with 40% respectively.
[read the full story...]
In this blog Manás Dave looks at a review of the prevalence of human papilloma virus (HPV) in oral potentially malignant disorders (OPMD). Although 52 studies were included one in five OPMDs being HPV positive is not a substantial link so teh findings need to be interpreted cautiously.
[read the full story...]
Manas Dave looks at a review of elective neck dissection (END) versus observation for the management of T1-2 oral squamous cell carcinoma. The review included 41 studies only 5 were RCTs the remainder being retrospective studies.
[read the full story...]
This review of the malignant transformation rate of oral lichen planus and associated risk factors included 33 studies. Using a strict definition the authors found a malignant transformation rate of 0.44%.
[read the full story...]
This UK multi-centre RCT of elective neck dissection(END) for early stage oral cancer found higher rates for overall and disease free survival in those patients having END.
[read the full story...]
This Cochrane review of interventions for preventing osteoradionecrosis of the jaws in adults with head and neck cancer undergoing curative or adjuvant (i.e. non-palliative) radiotherapy included 4 RCTs. The limited quality of the available studies means evidence regarding the interventions evaluated in this review is uncertain.
[read the full story...]
This review of the association between toombak use and oral leukoplakia and oral squamous cell carcinoma included 8 observational studies suggesting a strong association.
[read the full story...]
