High fluoride toothpaste for arresting and preventing root caries

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This randomised trial comparing 5000ppm fluoride tootpaste v 1450ppm paste in adults aged 60 and above demonstrated fewer new root canal lesions in the 5000ppm group at 2 years.

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Fluoride varnish for caries prevention in pre-school children

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This review of the effectiveness of fluoride varnish in reducing the risk of new caries in primary teeth included 20 studies suggesting modest effects in pre-school children.

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Fluoride for white spot lesion prevention during orthodontic treatment

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This review of professional topical fluoride application to prevent/reverse enamel white spot lesions during orthdontic treatment included 11 RCTs suggesting a reduction of in incidence of between 25–30% .

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Toothpaste: Does it inhibit plaque regrowth?

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This review of the effect of a regular fluoride dentifrice compared to water or saline on dental plaque inhibition using the 4-day non-brushing model included 9 studies and demonstrated a weak weak inhibitory effect on plaque regrowth with toothpaste use.

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Chlorhexidine-fluoride mouthwash efficacy

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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.

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Slow-release fluoride devices for caries prevention: insufficient evidence

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This review of slow-release fluoride devices for caries prevention updates an earlier Cochrane review of the topic. However no new trials have been identified providing insufficient evidence to assess their effectiveness.

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Fluoride supplements for pregnant women to prevent caries in their children

Pregnancy is a major life changing event for all women, but this study shows that women who are depressed during pregnancy are also at risk of reduced breastfeeding initiation and premature delivery

This Cochrane review of fluoride supplements during pregnancy for the prevention of caries in their children identified only a single trial which provided no evidence of caries prevention in their offspring.

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Silver diamine fluoride: effectiveness in older adults

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Three RCTs were included in this review of silver diamine fluoride for caries prevention in older adults. all 3 studies support teh effectiveness of SDF for root caries arrest and prevention.

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Silver Diamine Fluoride can arrest caries in children

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This review of silver diamine fluoride (SDF) to arrest caries included 19 studies and suggest that 38% SDF can arrest 81% ( 68-89%) of active caries. . However none of the available studies was at low risk of bias so the findings should be interpreted cautiously.

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