White spot lesions: Topical fluoride for prevention during fixed orthodontic treatment

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This Cochrane review update evaluates whether topical fluoride reduces the proportion of orthodontic patients with new demineralised lesions (white spot lesions). In included 10 studies finding some low certainty evidence that some topical fluorides reduced white spot lesions.

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Early childhood caries: Preventive interventions for pregnant and nursing mothers and other primary caregivers

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This Cochrane review asessing interventions with pregnant women, new mothers or other primary caregivers of infants in the first year of life for preventing early childhood caries included 17 RCTs .

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Root caries risk predictors

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This review of risk predictors of root caries was based on 16 cohorts. The findings suggest a number of risk predictors but only 4 of the included studies were considered to be of high quality.

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Enamel white spot lesions: self-application of topical fluorides for prevention and reversal

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This review of self-applied topical fluorides for the prevention reversal of enamel white spot lesions during fixed orthodontic treatment included 3 RCTs two of which were at high risk of bias.

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High fluoride toothpaste for arresting and preventing root caries

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This randomised trial comparing 5000ppm fluoride tootpaste v 1450ppm paste in adults aged 60 and above demonstrated fewer new root canal lesions in the 5000ppm group at 2 years.

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Fluoride varnish for caries prevention in pre-school children

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This review of the effectiveness of fluoride varnish in reducing the risk of new caries in primary teeth included 20 studies suggesting modest effects in pre-school children.

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Fluoride for white spot lesion prevention during orthodontic treatment

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This review of professional topical fluoride application to prevent/reverse enamel white spot lesions during orthdontic treatment included 11 RCTs suggesting a reduction of in incidence of between 25–30% .

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Toothpaste: Does it inhibit plaque regrowth?

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This review of the effect of a regular fluoride dentifrice compared to water or saline on dental plaque inhibition using the 4-day non-brushing model included 9 studies and demonstrated a weak weak inhibitory effect on plaque regrowth with toothpaste use.

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Chlorhexidine-fluoride mouthwash efficacy

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This review of the efficacy of a chlorhexidine mouthwash containing sodium fluoride compared to a chlorhexidine mouthwash alone includes 10 small short term studies that suggests the findings are similar for both preparations.

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Slow-release fluoride devices for caries prevention: insufficient evidence

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This review of slow-release fluoride devices for caries prevention updates an earlier Cochrane review of the topic. However no new trials have been identified providing insufficient evidence to assess their effectiveness.

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