Cochrane find insufficient evidence to support the implementation of depression prevention programmes

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Ioana Cristea summarises the latest Cochrane review on CBT, third-wave CBT and IPT based interventions for preventing depression in children and adolescents

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Risperidone versus placebo for people with schizophrenia

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Joanne Wallace summarises the recent Cochrane systematic review on risperidone versus placebo for schizophrenia, which concludes that the best available evidence does not show that the benefits of risperidone outweigh the harms.

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Pain during orthodontic treatment: non-pharmacological interventions

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14 trials were included in this Cochrane review of non-pharmacological interventions for orthodontic pain. The findings were inconclusive although there is some evidence that low-level laser therapy may help.

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Retrograde root filling: insufficient evidence for best material

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The Cochrane review of of materials for retrograde root filling identified 6 RCTs all at high risk of bias. The trials provide insufficient evidence to draw any conclusion as to the benefits of any one material over another so more high quality studies are needed.

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Root canal treatment: single or multiple visits?

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This Cochrane review update included 25 RCTs comparing single verses multiple root canal treatment approaches. They found no evidence to suggest that one treatment regimen is better than the other.

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Burning mouth syndrome: insufficient evidence for effectiveness of current treatments

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This update of a 2005 Cochrane review identified 23 RCTs but a limited number at low risk of bias so there is insufficient evidence to support or refute the use of any interventions in managing burning mouth syndrome.

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Cavity liners for posterior resin based composites?

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This Cochrane review of liners under posterior composite restoration included 8 RCTs identifying little evidence to show that they reduced sensitivity and no evidence of an effect on longevity of restorations.

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Oral care for critically ill ventilated patients

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38 RCTs were included in this Cochrane review update of oral health care in ventilated patients. High quality evidence was found to show that chlorhexidine mouthwash or gel reduces the risk of developing ventilator-associated pneumonia in critically ill patients from 25% to about 19%.

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Endodontic retreatment: Surgical or non-surgical approach?

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20 RCTs are included in this Cochrane review update of endodontic retreatment. The available evidence is of low quality so further research is needed to understand the effects of surgical versus non-surgical approaches, and to determine which surgical procedures provide the best results.

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Obstructive sleep apnoea: insufficient evidence for oral appliances in children

What other effects do nightmares and parasomnias have on sleep that could explain the association with future psychotic symptoms?

This Cochrane review to assess the effects of oral appliances or functional orthopaedic appliances for obstructive sleep apnoea in children only identified a single small trial which provided insufficient evidence to assess effectiveness.

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