How sleep changes across later life, and what it means for mental health

feat

A large UK Biobank study tracked sleep in over 77,000 adults. Here’s what the data reveals about age, sex and mood.

[read the full story...]

Changing sleep patterns linked to cognitive decline and dementia

feat

Two large cohorts (one UK, one Chinese) found shifting from optimal to non-optimal sleep or stopping napping linked to higher dementia risk. But reverse causation limits certainty about prevention.

[read the full story...]

Do psychiatric disorder genes overlap with their drug targets? And does this matter?

feat

Psychiatric disorders are highly heritable, but are the genes we identify in GWAS the same ones our medications target? This new study digs into the overlap and raises questions about how we develop treatments.

[read the full story...]

Are circadian rhythms the key to understanding our physical and mental health?

feat

Amy Ferguson discusses the latest research exploring the role of our circadian rhythms on our health, looking at different variants in the BMAL1 gene.

[read the full story...]

Mental health matters in premature menopause

feat

Dr Laura Naysmith summarises important new research on the mental health impacts of premature menopause.

[read the full story...]

The influence of the menopause in first onset of mental illness

darren-richardson-iY0GFYADmU0-unsplash

Katie Marwick on a new UK Biobank study which suggests that the two years either side of the final menstrual period represent a time of small increased risk for new onset bipolar and major depressive disorder.

[read the full story...]

Gut microbiome disruptions in depression: shifting the focus to metabolic signatures in blood

nadine-primeau--ftWfohtjNw-unsplash

Gerard Clarke explores a recent study which looks into the interplay of metabolome and gut microbiome in individuals with major depressive disorder.

[read the full story...]

Genetic risk for schizophrenia is associated with changes in heart structure and function

olivier-collet-1bRqiHGtPK0-unsplash

Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

[read the full story...]

Does what you eat affect how you feel?

ca-creative-kC9KUtSiflw-unsplash

Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

[read the full story...]

How living alone, loneliness and lack of emotional support link to suicide and self-harm

Lone,Man,In,Empty,Space,With,Dramatic,Shadow.,Looking,Down

Yutung Ng reviews a cohort study exploring the links between loneliness, living alone and emotional support with suicidality and self-harm.

[read the full story...]