Treating periodontitis to prevent heart disease – evidence unclear

heart attack

Only 1 trial at high risk of bias was included in this recent update of a 2014 Cochrane review of periodontal therapy for preventing cardiovascular disease (CVD) providing insufficient evidence to support or refute whether periodontal therapy can prevent the recurrence of CVD in the long term in patients with chronic periodontitis.

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Sleep bruxism: risk factors


This review of risk factors for sleep bruxism identified 9 studies involving a total of 12,454 patients. Strong associations were found for sleep bruxism, GERD and a gene related to serotonergic neurotransmission.

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Antibiotics as an adjunct to the non-surgical periodontal treatment of smokers

Smoking man

Mark-Steven Howe looks at a systematic review of the effectiveness of adjunctive antibiotics in smokers undergoing non-surgical periodontal treatment. While a statistical benefit was noted it was not considered to be clinically relevant.

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Severe mental illness in offspring may not be linked to smoking during pregnancy


Andrew Jones considers a recent cohort study that looks into the associations between maternal smoking during pregnancy and severe mental illness in offspring.

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Smoke-free policy in psychiatric hospitals associated with reduction in physical violence


Olivia Maynard reports on a new study in The Lancet Psychiatry that explores the effect of implementing a smoke-free policy on physical violence in a psychiatric inpatient setting, which has some surprising findings.

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Tobacco smoking, cognition and first episode psychosis: time for a rethink?


Marcus Munafo appraises a recent cross sectional study of tobacco smoking and its association with cognition in first episode psychosis patients.

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Nicotine reverses hypofrontality in animal models of addiction and schizophrenia

Screen Shot 2017-03-06 at 17.02.56

Marcus Munafo looks at a complex and sophisticated series of experiments that provide further insight into the relationships between genetic risk, cigarette smoking and schizophrenia.

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NICE one? Is NHS guidance on substance misuse fit for purpose?


Ian Hamilton explains why the National Institute for Health and Care Excellence have missed a trick by not updating their 2007 guidance on psychosocial interventions for substance misuse.

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OCD risk may increase following perinatal complications


Alan Underwood summarises a population based cohort study of 2.4 million Swedish children, which highlights links between perinatal risk factors such as smoking during pregnancy, and later development of obsessive compulsive disorder.

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Oral Clefts and maternal smoking associated suggests review

shutterstock_91019771 Clefts

This review examined the link between maternal smoking and oral clefts. 29 studies ( 6 Cohorts & 23 case control studies) were included and a positive association has noted. No quality assessment of the included studies was presented.

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