Probiotics for depression: robust and compelling evidence?

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A team from the Centre for Affective Disorders at King’s College London appraise a new systematic review on probiotics for depression, which claims to have found robust and compelling evidence that these supplements can alleviate depressive symptoms.

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Medication for self-harm: new Cochrane review finds very limited evidence to support its use

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Dochka Hristova reports on a new Cochrane review of pharmacological interventions for self-harm in adults, which looks at the treatment effect on repetition of self-harm of antidepressants, antipsychotics, mood stabilisers and dietary supplements.

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Folic acid for depression: RCT finds no effect on reducing incidence of depression or bipolar

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Elly O’Brien summarises a recent RCT of folic acid for depression, which explores whether mood disorders can be prevented in young people at familial risk. The trial finds no evidence that folic acid supplementation reduces the incidence of mood disorders compared to those taking placebo.

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CAM: Many of us are using it, despite poor evidence. Whats going on?

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Complementary and alternative medicine (CAM) therapies are often perceived to be as effective as conventional treatments, more “natural”, less expensive, have fewer side-effects and are easily available without a prescription. But do these perceptions match up with the reality? Can CAM therapies be helpful additions to conventional treatments? This alludes to an interesting sociological question [read the full story…]