Novel Psychoactive Substances: bridging the knowledge gap

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Derek Tracy takes a first look at the Novel Psychoactive Substances in the UK Project; an NIHR-funded empirical and conceptual review that recommends research priorities in the field.

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Novel Psychoactive Substances: important information for health professionals

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Harry Sumnall, Ian Hamilton and Mark Monaghan provide an overview of Novel Psychoactive Substances (NPS) aimed at health professionals and others who work with people who use these new psychoactive substances.

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Methylphenidate for ADHD: have Cochrane got it wrong this time?

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Chris Hollis appraises a recent Cochrane systematic review, which casts doubt over the quality of trial evidence and the clinical effectiveness of Methylphenidate for ADHD.

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Stimulants reduce risk of injuries in children with ADHD

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Joff Jones highlights an important public health finding from a recent prospective cohort study about the effect of stimulant drugs on the risk of injuries in children with ADHD.

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Combined methylphenidate and citalopram may help older people with depression recover faster

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Lisa Burscheidt summarises a recent randomised controlled trial of combined methylphenidate and citalopram for depression in older people, which presents promising but limited findings.

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The adverse effects of psychiatric drugs and emergency department visits

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A new study finds that psychiatric medications are implicated in many adverse drug events treated in US emergency departments. Nearly 1 in 10 of all adverse drug event visits to emergency departments are due to psychiatric drugs, including antidepressants, antipsychotics, lithium salts, sedatives, anxiolytics and stimulants.

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Cutting across diagnostic categories: Does stimulant medication improve ADHD symptoms in children with autism spectrum disorder?

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Until fairly recently, it was thought that autism spectrum disorder (ASD; previously known as PDD or pervasive developmental disorder) and attention deficit hyperactivity disorder (ADHD) were two entirely separate childhood-onset conditions and that they could not both be diagnosed in one individual. Numerous studies in the last decade have shown that, in reality, a number of [read the full story…]

Systematic review of dropout rates from clinical trials of methylphenidate for adult ADHD

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Attention deficit hyperactivity disorder (ADHD) is characterised by inattention, excessive activity levels and impulsive behaviours. Although it is an early developmental condition and is associated with childhood, in many instances, it is a lifelong condition. ADHD in adulthood is increasingly being recognised. Clinical guidelines and research suggest that the stimulant drug methylphenidate can reduce ADHD [read the full story…]

Brain imaging reveals different pattern of activity in ADHD, which is partly normalised by medication

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How brain imaging can help us understand mental health problems and their treatment is another service that the mental elf team will hopefully be able to offer.  By blogging about interesting new studies we hope to help you pick up a wee bit of how MRI, CT, EEG and MEG adds to our understanding.  While [read the full story…]

Many children taking ADHD drugs say that it helps them control their behaviour and make better decisions, according to new survey

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The ADHD Voices (Voices On Identity, Childhood, Ethics and Stimulants) report was published yesterday and received a significant amount of press coverage. The outcomes of this work are a 46-page report and 18-minute video, that aim to inspire a fresh public conversation about the ethics of Attention Deficit/Hyperactivity Disorder (ADHD) diagnosis and stimulant drug treatments [read the full story…]