Medication for ADHD: what works for adults, adolescents and children

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Dean Connolly is impressed by a recent systematic review and network meta-analysis, which compares the efficacy and tolerability of medication for ADHD in children, young people and adults.

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Novel Psychoactive Substances: bridging the knowledge gap

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Derek Tracy takes a first look at the Novel Psychoactive Substances in the UK Project; an NIHR-funded empirical and conceptual review that recommends research priorities in the field.

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Novel Psychoactive Substances: important information for health professionals

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Harry Sumnall, Ian Hamilton and Mark Monaghan provide an overview of Novel Psychoactive Substances (NPS) aimed at health professionals and others who work with people who use these new psychoactive substances.

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Cardiovascular safety of methylphenidate

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Samuele Cortese considers the findings of a recent nationwide self controlled case series study of the cardiovascular safety of methylphenidate use in children and young people with ADHD.

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Amphetamines and methylphenidate for paediatric ADHD: meta-analysis of n-of-1 trials

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Samuele Cortese publishes his debut Mental Elf blog on a meta-analysis of n-of-1 trials, which shows that amphetamine derivatives and methylphenidate are superior to placebo, in the short term, for paediatric ADHD.

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Methylphenidate for ADHD: have Cochrane got it wrong this time?

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Chris Hollis appraises a recent Cochrane systematic review, which casts doubt over the quality of trial evidence and the clinical effectiveness of Methylphenidate for ADHD.

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Commonly prescribed psychiatric drugs: do they work?

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John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.

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Stimulants reduce risk of injuries in children with ADHD

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Joff Jones highlights an important public health finding from a recent prospective cohort study about the effect of stimulant drugs on the risk of injuries in children with ADHD.

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Combined methylphenidate and citalopram may help older people with depression recover faster

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Lisa Burscheidt summarises a recent randomised controlled trial of combined methylphenidate and citalopram for depression in older people, which presents promising but limited findings.

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The adverse effects of psychiatric drugs and emergency department visits

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A new study finds that psychiatric medications are implicated in many adverse drug events treated in US emergency departments. Nearly 1 in 10 of all adverse drug event visits to emergency departments are due to psychiatric drugs, including antidepressants, antipsychotics, lithium salts, sedatives, anxiolytics and stimulants.

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