Are antidepressants safe? A new umbrella review of observational studies suggests they are, but we need more accurate data

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Andrea Cipriani and Anneka Tomlinson scrutinise a brand new umbrella review of the associations between antidepressants and adverse health outcomes, which suggests that antidepressants are safe for most people who experience mental health difficulties.

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What causes Autistic Spectrum Disorder?

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Ben Janaway explores a recent review in JAMA Psychiatry on the emerging clinical neuroscience of Autism Spectrum Disorder.

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Intranasal esketamine for treatment-resistant depression: the first clinical study

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Jodi Rintelman writes her debut elf blog on the first randomised controlled trial on the efficacy and safety of intranasal esketamine as an adjunctive treatment to antidepressants for treatment-resistant depression.

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Who gets bullied? Using genetic information to identify individual vulnerabilities

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Lucy Bowes explores a multi-polygenic score approach to identifying individual vulnerabilities associated with the risk of bullying, which suggests that depression, ADHD, risk taking, BMI and intelligence are independently associated with exposure to bullying.

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Genetic predictors of depression trajectories in adolescence

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Megan Skelton explores a study that uses polygenic scores in the context of longitudinal developmental data, to characterise developmental trajectories and the role of neuropsychiatric genetic risk variants in early-onset depression.

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Lack of wealth may increase our risk of dementia

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A group of UCL Mental Health Masters students summarise a recent cohort study of the individual and area-based socioeconomic factors associated with dementia incidence in England.

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Victims of crime with mental illness: differences between Denmark and the US

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Chris Millar writes his debut blog on a recent paper that explores the link between mental illness and being subjected to crime in Denmark and the United States. This blog asks: how much do poverty and the safety net matter? There are some important implications for policy makers.

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Crime victimisation: vulnerability increased after onset of mental illness

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Danny Whiting writes his debut elf blog on a recent Danish study that uses police data to measure the risk of being subjected to crime, including violent crime, after onset of mental illness.

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Is the incidence of schizophrenia in South-East London really 10 times higher than in Santiago, Spain?

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Vishal Bhavsar reviews an EU study of nearly 3,000 people across 6 EU countries, looking at the treated incidence of schizophrenia and psychotic disorders. It helps us better understand who gets psychosis, when, and where.

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Persistent and severe postnatal depression predicts adverse outcomes in children

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Sophie Graham and Jennifer Burgess explore the associations between persistent and severe postnatal depression in mothers and mental health and educational outcomes in their offspring.

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