What can genetics tell us about the link between cannabis and schizophrenia? #MHQT

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Suzi Gage summarises a recent GWAS of lifetime cannabis use, which reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Interesting new evidence ahead of our Mental Health Question Time #MHQT event in London tomorrow.

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The genetics of depression (and anxiety!)

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Thalia Eley shares her thoughts on a recent Nature genome-wide association study of depression phenotypes in the UK Biobank, which uses different definitions of depression to provide more tractable targets for future genetic studies.

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Understanding the genetics of antipsychotic treatment response

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Marcus Munafo looks at a Chinese genome-wide association study that claims to have identified some of the genes associated with response to antipsychotic treatment.

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Psychiatric genomics: an update and an agenda

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Marcus Munafo comments on a review of the work of the Psychiatric Genomics Consortium, which in recent years has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders.

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Genetics of depression: risk factors and protective factors

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Marcus Munafò reports on a new genome-wide association study that identifies 44 risk variants and helps us to further refine the genetic architecture of major depressive disorder.

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Schizophrenia and genetics: a new landmark study

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Genome-wide association studies have proved extremely successful in identifying reliable genetic associations with a number of disease outcomes, but until now studies of psychiatric outcomes have lagged behind. This latest schizophrenia study is therefore an important advance.

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