A Danish RCT of the 10-week PEER (Paths to Everyday Life) group programme found meaningful gains in personal recovery, functioning and quality of life for adults with mental health difficulties.
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A major new RCT of Structured Psychological Support finds brief therapy offers no meaningful benefit over usual care for people with personality disorders.
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The EPISODE trial of psychedelic-assisted therapy for ‘treatment-resistant depression’ finds only modest effects, with a few clear responders, but lingering methodological questions.
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A single dose of tocilizumab cleared inflammation in depressed patients, but did it ease their symptoms? A proof-of-concept RCT with cautious promise.
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Up to 80% of people with personality disorder report neglect or abuse. So why aren’t we offering them trauma-focused therapy? A new trial has some answers.
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A small proof-of-principle trial suggests MDMA-assisted therapy may be feasible and effective for depression, but open-label design and a highly pre-treated sample urge caution.
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New evidence shows Melodies for Mums outperforms standard community activities in reducing postnatal depression, with sustained effects lasting six months after the singing ends.
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New research suggests that weight gained in the first 12 weeks of antipsychotic treatment is the biggest driver of long-term obesity in psychosis.
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Can training your brain’s reward circuits strengthen your immune response to vaccination? A new randomised controlled trial offers some fascinating early clues.
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A new RCT tested text message CBT for generalised anxiety in young adults, with promising results. But is it ready for clinical practice?
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