Depression in later life: who benefits most from antidepressants plus exercise?

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Linda Gask explores an RCT of physical exercise for depression in later life, which considers the best way to customise the intervention for primary care.

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Exercise and iCBT for depression: how do ‘alternative’ treatments compare to usual care?

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Bethan Davies publishes her debut blog on a recent Swedish RCT of exercise and internet-based cognitive-behavioural therapy for depression.

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Diet and depression: can we eat our way out of clinical depression? The ‘SMILES’ trial

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Murtada Alsaif chews over the SMILES RCT of dietary improvement for adults with major depression, which reports encouraging results for healthy diet in people with depression.

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Targeting unhelpful repetitive negative thinking in young people to prevent anxiety and depression

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Michelle Moulds publishes her debut blog on a recent randomised controlled trial about the prevention of anxiety disorders and depression by targeting excessive worry, rumination and repetitive negative thinking in young adults.

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Collaborative care may help older adults with subthreshold depression: CASPER trial

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Ben Hannigan summarises the new CASPER trial of collaborative care versus usual care for older adults with subthreshold depression.

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Psychotherapies for depression in children and adolescents: all of equal IMPACT?

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Jasmin Wertz summarises the recently published IMPACT trial, which found that CBT, short-term psychoanalytical psychotherapy and brief psychosocial interventions (psychoeducation) were all equally effective in treating depression in children and young people.

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Omega-3 fatty acids to prevent psychosis: the importance of replication (NEURAPRO trial)

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Raphael Underwood summarises the NEURAPRO trial, which concludes that Omega-3 fatty acids are no better than placebo at preventing transition to psychosis in young people at ultrahigh risk for psychotic disorders.

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Virtual Reality for Social Anxiety Disorder: can we get fully immersed in this treatment just yet?

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Joe Barnby publishes his debut elf blog on a recent randomised controlled trial of virtual reality compared with in vivo exposure in the treatment of social anxiety disorder.

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Antipsychotics for delirium in palliative care: new RCT suggests non-drug alternatives are needed

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Samei Huda highlights a recent RCT of antipsychotics (risperidone and haloperidol) versus placebo for symptoms of delirium in palliative care, which suggests we need non-drug alternatives for this group of patients.

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Comparing applets and oranges: barriers to evidence-based practice for app-based psychological interventions

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A repost of Simon Leigh’s excellent recent article in Evidence-Based Mental Health on the clear need for consensus and guidance for app developers, as to which patient-reported outcome measures should be used when developing mental health apps.

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