Transdiagnostic and disorder-specific anxiety disorder treatments have equivalent treatment effects #TransDX2018

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Jill Newby and Peter Norton blog an RCT on the unified protocol for transdiagnostic treatment of emotional disorders compared with diagnosis-specific protocols for anxiety disorders.

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Preventive cognitive therapy when continuing or tapering off antidepressants

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Linda Gask is encouraged by the findings of a new high quality RCT (the DRD study), which compares preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in the prevention of depressive relapse or recurrence.

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Is Cannabidiol (CBD) an effective antipsychotic?

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Luke Sheridan Rains publishes his debut blog on a recent multicentre RCT of Cannabidiol (CBD) as an adjunctive therapy for people with schizophrenia, which suggests that CBD had a beneficial, but modest impact on positive psychotic symptoms and severity of illness when used alongside existing antipsychotics.

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Collaborative care for depression and physical multimorbidity: clinically and cost-effective over the long term

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Gemma Shields summarises the findings of a cluster RCT looking at the long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental-physical multimorbidity.

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Low dose Amisulpride for very late onset schizophrenia-like psychosis: the ATLAS study

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Elwira Lubos summarises the recent ATLAS RCT of antipsychotic treatment for very late-onset schizophrenia-like psychosis, which provides evidence for the effectiveness of a very low dose of Amisulpride (100 mg).

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After the crisis: self-management and peer-support

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Jenny Collom, Maria Giorgalli and Derek Tracy welcome a new RCT published yesterday in The Lancet which demonstrates the benefits of peer-supported self-management for people discharged from a mental health crisis team.

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Incredible Years Teacher Classroom Management: STARS trial suggests benefits for children’s mental health

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Neil Humphrey is impressed by the STARS cluster randomised controlled trial published today in Psychological Medicine, which evaluates the effectiveness and cost-effectiveness of the Incredible Years Teacher Classroom Management programme in primary school children.

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QbTest is not a diagnostic tool, but it can increase the efficiency of ADHD diagnosis

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Samuele Cortese is impressed by a recent RCT of QbTest: a computerised test of attention and activity, which can improve diagnostic decision-making in children and young people with suspected ADHD.

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Individual Placement and Support works for US veterans with PTSD

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Harry Palmer from the Centre for Mental Health summarises a recent RCT, which suggests that Individual Placement and Support helps veterans with PTSD to achieve steady work better than the US Veteran Affairs’ transitional work programme.

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Positive Behaviour Support: RCT finds no effect, but fidelity is poor

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Dave O’Regan reports on a recent cluster RCT of staff training in positive behaviour support to reduce challenging behaviour in adults with intellectual disability.

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