The genetics of depression (and anxiety!)

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Thalia Eley shares her thoughts on a recent Nature genome-wide association study of depression phenotypes in the UK Biobank, which uses different definitions of depression to provide more tractable targets for future genetic studies.

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Estimating heritability in 5 psychiatric disorders: a 21st Century family study

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It has long been established that psychiatric disorders have a genetic component. In the early days of genetic research, twin and family studies were used to estimate heritability (the proportion of variance explained by genetic factors). The Psychiatric Genetics Consortium has recently published a paper in Nature Genetics to assess the heritability and co-inheritability (relationship between [read the full story…]