Can proteomics improve our prediction of depression remission?

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Jonas Hagenberg discusses new insights into the possible use of proteomics (the large-scale study of proteins) for improving our prediction of depression remission.

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Antidepressant withdrawal: recommendations for support from people with lived experience

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Hannah Bowers summarises a study exploring the need for antidepressant withdrawal support, from 708 survey respondents with lived experience.

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Capturing the lived experience of depression

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Charlotte Walker blogs about a recent World Psychiatry ‘bottom-up review’ on the lived experience of depression; co-written by experts by experience and academic researchers.

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Are transdiagnostic mental health interventions the future of treatment?

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Isabeau Tindall summarises a recent meta-analysis by Pim Cuijpers and colleagues investigating the effective of transdiagnostic treatments for depression and anxiety.

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Is anxiety a gateway to other mental health problems? Comorbidities with depression and other anxiety disorders

Results from the current study largely replicated findings from the NESDA dataset in demonstrating that those with comorbid anxiety and/or depression have more severe presentations that anxiety or depression alone.

Nina Higson-Sweeney summarises a study using data from the UK-based GLAD and COPING NBR cohorts to investigate factors associated with anxiety disorder comorbidity with anxiety and depression.

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Self-stigma for people with depression: systematic review presents global prevalence data, risk factors and protective factors

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Pattie Gonsalves blogs about the stigma that people with depression can sometimes feel towards themselves; summarising a recent systematic review that estimates the global prevalence of depression self-stigma, alongside risk factors and protective factors.

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Clinical severity and instability as predictors for psychiatric hospitalisation: can one size fit all? 

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Florian Walter summarises a retrospective cohort study published in The Lancet Psychiatry that investigates whether early trajectories of clinical global impression severity can transdiagnostically predict later psychiatric hospitalisation.

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Brief interpersonal therapy may help relieve maternal depression during pregnancy

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In this blog, Francesca Kingston summaries a clinical trial from the US Care Project, which investigated whether depression can be reduced during pregnancy and before birth using a brief, safe intervention.

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Gut microbiome disruptions in depression: shifting the focus to metabolic signatures in blood

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Gerard Clarke explores a recent study which looks into the interplay of metabolome and gut microbiome in individuals with major depressive disorder.

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Turn on, or tune out? Is psilocybin assisted therapy close to becoming a first-line treatment for depression?

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James Rucker and Sameer Jauhar summarise a recent RCT on the effectiveness of psilocybin assisted therapy versus escitalopram assisted therapy for major depressive disorder.

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