Towards a symptom-based diagnosis of psychotic spectrum disorders?

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Stefanie Sturm critically analyses a recent paper that suggests a symptom-based continuum of psychosis explains cognitive and real-world functional deficits better than traditional diagnoses.

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Risperidone and aripiprazole: genotype, metabolism and dosage

CYP2D6 genotyping before starting treatment might be valuable in clinical practice for individualising risperidone and aripiprazole treatment.

Dolly Sud writes her debut elf blog on a recent retrospective analysis, which compares dose changes of risperidone and aripiprazole with patients’ individual genotype.

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Service user experiences of dissociation

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A team of mental health staff from the University of Edinburgh write a joint blog on a recent qualitative study about the experience of dissociation in people with psychosis.

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Antipsychotics and metabolic function in people with schizophrenia

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Peter Haddad and Sami Ouanes review a network meta-analysis of the impact of antipsychotic drugs on metabolic function in people with schizophrenia.

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In harm’s way: psychiatric diagnosis and risks of being subjected to and perpetrating violence

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Sarah Steeg discusses a cohort study finding that people with a psychiatric diagnosis are 3-4 times more likely to be a victim or perpetrator of violence.

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Cancer screening disparities in people with mental illness

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Emily Peckham from the Closing The Gap Network writes her debut blog on a new systematic review, which finds that people with mental illnesses were less likely to receive screening for cancer compared to the general population.

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Is schizophrenia a by-product of human evolution?

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Muzaffer Kaser writes his debut elf blog on a recent study, which looks at evolutionary modifications in human brain connectivity associated with schizophrenia.

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The Trial: pharmacotherapy versus psychotherapy for schizophrenia – how do trials compare?

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Keith Laws looks at a systematic review of patient and study characteristics, which asks: are randomised controlled trials on pharmacotherapy and psychotherapy for positive symptoms of schizophrenia comparable?

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Long-term outcomes of childhood sexual abuse #ISTSS2019

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Raphael Underwood summarises a recent umbrella review (a synthesis of meta-analyses), which aimed to evaluate the current literature regarding childhood sexual abuse and long-term outcomes (psychosocial outcomes, psychiatric diagnoses and physical health outcomes).

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Cognitive functioning in psychosis: is neuropsychological decline continuous, generalised, and specific to schizophrenia?

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Emmeline Lagunes Cordoba and Derek Tracy explore a case control study that looks at cognitive change in people with schizophrenia and other psychoses in the decade following the first episode.

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