Inflammation and depression: new insights into sex differences in adolescents

Illustration set of 9 different faces of all sexes and races . Also available in other sets.

Sophie Fairweather explores a recent paper which suggests that the inflammatory cytokines IL-2 and IL-6 are associated with both the risk of developing depression, and with depression severity, although this relationship is modified by sex.

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Anti-inflammatory treatments for youth depression: promising but not yet implementable

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Céline Wessa reports on a recent systematic review of pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms, which has some promising results.

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Can proteomics improve our prediction of depression remission?

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Jonas Hagenberg discusses new insights into the possible use of proteomics (the large-scale study of proteins) for improving our prediction of depression remission.

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Genetic risk for schizophrenia is associated with changes in heart structure and function

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Nadine Parker and Ole Andreassen summarise a recent UK population-based cohort study, which looks at the impact of polygenic risk for schizophrenia on cardiac structure and function in over 32,000 people.

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Does what you eat affect how you feel?

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Daisy Crick summarises a recent paper on the casual relationship between polyunsaturated fatty acids and depression.

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Blood-based inflammatory markers in acute vs chronic schizophrenia

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Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

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Inflammation and depression in young people #ActiveIngredientsMH

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Yara Toenders and Lianne Schmaal consider the links between inflammatory dysregulation and depression in young people, by reviewing a recent study carried out by researchers in the US, and also by presenting the results of their own recent #ActiveIngredientsMH review, which was funded by the Wellcome Trust.

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Autoimmune and autoinflammatory diseases associated with higher risk of eating disorders

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Francesca Solmi appraises and summaries a recent population-based cohort study that explores the links between eating disorders and autoimmune and autoinflammatory diseases.

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Biological markers for treatment response in first episode psychosis

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Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress.

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