Off-label antidepressants: limited evidence to support their use

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John Baker reports on Canadian study looking at prescriptions of off-label antidepressants in primary care, which concludes that when antidepressants were used outside of their licence, there was usually not strong evidence supporting the respective indication.

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A PACE-gate or an editorial without perspectives?

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This commentary by Kjetil Gundro Brurberg, Signe Flottorp and Aase Aamland was written in response to an invitation from the Editor of the Journal of Health Psychology, who subsequently decided not to publish it. In the interest of science and open debate, we have decided to publish the commentary.

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Severe mental illness in offspring may not be linked to smoking during pregnancy

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Andrew Jones considers a recent cohort study that looks into the associations between maternal smoking during pregnancy and severe mental illness in offspring.

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Elves under the microscope: does elf promotion increase research uptake by health professionals?

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Sarah Knowles reports on a survey and brief intervention study of the National Elf Service across the Oxford Health NHS Foundation Trust, which sheds some light on how best to increase research uptake in mental health professionals.

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Right People, Right Questions: new survey on young people’s mental health #youngpeopleMHQ

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Today we are announcing a major new survey that will help prioritise research questions for young people’s mental health over the coming years. The Right People, Right Questions project is about looking for your unanswered questions on young people’s mental health that can be answered by research. We want to hear from 11-25 year olds with experience of mental health issues, their parents or carers, if you work with young people, or if you have another interest in the mental health of young people.

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How does age at onset affect outcomes in schizophrenia?

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Geoff Davies publishes his debut elf blog about a recent systematic review and meta-analysis looking at age at onset and the outcomes of schizophrenia.

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Tetris for PTSD: behavioural intervention unlikely to vaccinate against intrusions

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Ioana Cristea disputes the claims of a recent proof-of-concept RCT, which aims to prevent intrusive memories after trauma via a brief intervention involving Tetris computer game play in the emergency department.

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Investigating the link between loneliness and sleep quality in young people

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Ahmed Al-Shihabi and Farhana Mann report on a recent twin study that explores the links between loneliness and sleep quality in young adults.

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Trajectories of depressive symptoms in children and adolescents

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Jess Bone on a systematic review of longitudinal studies, which explores the different trajectories of depressive symptoms in children and adolescents, and the factors that might help predict or protect young people.

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Guided self help and cCBT for OCD: OCTET finds low adherence and uncertain fidelity

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Alan Underwood reports on the new OCTET trial published last week, which fails to find any support for the use of low-intensity guided self-help or computerised CBT for people with obsessive compulsive disorder (OCD).

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