Lamotrigine in the maintenance treatment of bipolar disorder

Lamotrigine, an anticonvulsant drug, is licensed in the United States for the maintenance treatment of bipolar I disorder and in the UK to prevent depressive episodes in bipolar disorder. Hashimoto and colleagues (2021) performed a Cochrane Intervention Review to explore whether lamotrigine is effective and safe compared to the most established maintenance treatment, lithium, and placebo.

Michael Ostacher critically appraises and summarises a recent Cochrane systematic review, which presents the latest best evidence on the efficacy of lamotrigine in the maintenance treatment of bipolar disorder.

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“It’s like putting a penguin on the floor”: what can the perspectives of youth with autism teach us about social inclusion? #ActiveIngredientsMH

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Xanthe Hunt and Jason Bantjes consider the perspectives of autistic young people affected by social exclusion, and present early findings from their new active ingredients review which looks at the role of social inclusion interventions in improving adolescent mental health.

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Why doesn’t parent involvement help treat children with anxiety?

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In her debut blog, Jeanne Wolstencroft summarises a systematic review finding that parental involvement in therapy doesn’t help treat children with anxiety.

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Supporting the supporters: peer support in early intervention in psychosis

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In her debut blog, Natalie Kashirsky explores a qualitative study finding valuable mechanisms of peer support in early intervention in psychosis services.

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Infrastructures fit for purpose? The complex challenges in sharing mental health data

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Louise Arsenault provides a fascinating overview on the challenges and complexities of sharing mental health data in the UK.

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Childhood trauma, bullying-victimisation and the mental health of LGBTQ+ individuals

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Andie Ashdown and Theophanis Kyriacou review a study from the Netherlands that looks at the links between childhood trauma, bullying-victimization and mental illness in people from sexual minority groups.

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The 4M model for promoting student mental health: mindfulness, movement, meaning and moderator-based interventions

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In her debut blog, Snigdha Dutta explores the 4M model for promoting university student mental health, explored by a recent systematic review which suggests that a combination of mindfulness, movement, meaning, and moderator-based interventions may help.

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Parental loss and grief in childhood linked to an increased risk of depression in adulthood #ActiveIngredientsMH

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In her debut blog, Lauren Breen summarises a paper relevant to her Active Ingredients project, which seeks to understand the impact that grief reduction interventions can have on reducing anxiety and depression in young people aged 14-24 years.

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How are loneliness, social isolation and frailty linked with age?

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Clarissa Giebel explores a recent prospective study using data from the English Longitudinal Study of Ageing (ELSA), which looks at the longitudinal relationship between loneliness, social isolation, and frailty in older adults in England.

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