Results: 1122

For: meta-analysis

Occlusal caries diagnostic measures

occlusal caries, molar teeth

This review of the diagnostic performance of commonly used methods for occlusal caries diagnoses included 37 studies the majority (29) being conducted in-vitro. While summary diagnostic performance datafor a muber of diagnistic methods is provided it should be treated cautiously as th data is limited in many areas.

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Which retrograde root filling material?

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This Cochrane review update of different materials used for retrograde root filling in children and adults requiring retrograde filling included 8 RCTs. However the studies are all at high risk of bias so provide insufficient evidence for the benefits of any one material.

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Periodontitis: Locally delivered anti-microbials as an adjunct to surgical periodontal treatment

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This review of the effectiveness of locally delivered adjunctive antibiotic treatment during periodontal surgery on clinical outcomes included 9 RCTs. While the findings suggested that adjunctive locally delivered antibiotics could improve some clinical sutcomes they evidence was limited and of very low certainty.

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Osteoradionecrosis and tooth extraction before radiotherapy

radiotherapy

This review of the osteoradionecrosis rate in patients with head and neck cancer having toothth extraction performed before radiotherapy included 8 mainly retrospective studies. The pooled incidence rate was estimated at 2.2% (95% CI: 0.6% to 3.9%) although none of the studies controlled for other risk factors.

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Platelet-rich fibrin and third molar post extraction problems

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This review of the effectiveness of leukocyte-and platelet-rich fibrin (L-PRF) and advanced-platelet-rich fibrin (A-PRF) in mandibular third molar extraction included 10 RCTs. While the findings suggest some benefits the studies are small and limited in number so the findings should be interpreted cautiously.

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Class II restorations in primary molars

shutterstock_72680830 - erupting incisors & caries

This review comparing compare the success rate of five tooth-coloured materials for class II restorations in primary molars included 10 RCTs. No differences in failure rates were seen for composite resin,resin-modified glass ionomer cement or compomers although all included studies were at high risk of bias.

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Psychotherapy and antidepressant tapering can help people at risk of depression relapse, but more evidence needed before we can provide personalised treatment

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Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.

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Vital pulp therapy in permanent teeth

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This review aimed to evaluate the association of preoperative factors or intraoperative factors with treatment outcomes of vital pulp therapy. 14 RCTs were included with the findings indicating a 93.2% (95%CI; 91-6% to 94.9%) success rate using contemporary bioceramic material based on low certainty evidence.

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Peri-implantitis: Are locally administered antibiotics effective?

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This review of the effectiveness of locally administered antibiotics in the treatment of peri-implantitis included 12 small studies 7 of which were RCTs. While the findings suggest a small additional benefit with antibiotic use however the clinical importance of this is debatable.

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Oral mucositis: Risk factors in paediatric oncology patients

The authors suggest a number of factors that may lead to increased prevalence, including depression, childhood trauma, low self-esteem and genetic risk.

Manas Dave takes a look at this review aiming to identify the potential risk factors associated with the development of oral mucositis in paediatric patients. While a range of risk factos are higlighted it is worth noting that 80-100% of all children having chemotherapy experience some degree of mucositis.

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