Medication-related osteonecrosis of the jaw (MRONJ): Prevention and treatment

osteonecrosis

This Cochrane review update of interventions for the prevention or treatment of medication-relatesd osteonecrosis of the jaw (MRONJ) included 13 RCTs. However the studies provided insufficient to either claim or refute a benefit of the interventions tested for prophylaxis or treatment of MRONJ.

[read the full story...]

Tooth extraction prior to head and neck radiotherapy and osteoradionecrosis risk

shutterstock_84141019

28 mainly retrospective studies were included in this review which aimed to determine if tooth extraction prior to head and neck radiotherapy (RT )is associated with a reduced risk of developing osteoradionectosis (ORN). The findings showed a significant association of post-RT dental extractions with the risk of ORN development, odds ratio = 1.98 (95%CI: 1.17 to 3.35. However the certainty of the evidence was low to moderate.

[read the full story...]

Third molar surgery and antibiotics to prevent infection

shutterstock_31846396

This review and infection of dry socket after third molar surgery identified 58 RCTs of whihc 34 contributed to a meta-analyses. The findings indicated that metronidazle and amoxicillin did reduce infection but the findings were of low certainty.

[read the full story...]

Intraosseous injection or inferior alveolar nerve block for third molar surgery?

shutterstock_17571817- injection

This review comparing the anaesthetic efficacy of intraosseous injection(IO) and conventional inferior alveolar nerve block (INAB) in mandibular third molar surgery included 4 small RCTs. The findings suggest no significant difference between IO and INAB techniques.

[read the full story...]

Ibuprofen prior to lower third molar removal

shutterstock_75860806

This review of the effect of pre-emptive ibuprofen on post-operative pain after lower third molar surgery included 5 RCTs. Only one of the included studies was at low risk of bias so there is insufficient evidence to support the routine use of pre-emptive ibuprofen to reduce post-operative pain after lower third molar removal

[read the full story...]

Cyanoacrylate tissue adhesive in postoperative palatal pain management

Gingival graft

This review assessing the effect of cyanoacrylate tissue adhesive (CTA) in the management of palatal wound healing and post-operative pain after epithelialised gingival graft harvesting included just 4 small RCTs. While the findings suggest a potential benefit with CTA both the quantity and quality of the available evidence is very limited.

[read the full story...]

Superior labial frenum and maxillary midline diastema

shutterstock_54584944  - mixed dentition

This review aiming to provide information about the association between a superior labial frenum and maxillary midline diastema included 11 cross-sectional studies. The findings suggest that papillary and papillary penetrating frenum may be associated with maxillary midline diastema but the evidence is limited.

[read the full story...]

Third molar surgery – Er:Yag lasers and post-operative problems

shutterstock_37849495

This review of the effectiveness of Er:YAG lasers in reducing pain, oedema and trismus compared to rotary instruments for the removal of impacted lower third molars included 6 small studies only one of which was at low risk of bias. The findings suggest a reduction in swelling and a small reduction in pain however the findings should be viewed cautiously because of the limited amount and quality of the evidence.

[read the full story...]

Maxillary sinus augmentation – relative performance of available biomaterials and the challenge of small studies

Sinus Lift

Mark Steven Howe takes a detailed look at this Bayesian network meta-analysis (NMA) assessing the relative performance of diffferent biomaterials used for maxillary sinus augmentation. 34 RCTs with 28 different treatment options providing a large number of potential pairwise comparisons although only a small number used direct data. The findings suggest little difference beween the various biomaterials but the available studies are small with only 5 being at low risk of bias.

[read the full story...]

Platelet-rich fibrin to reduce post-operative complications of lower third molar removal

shutterstock_75626410

This review of platelet-rich fibrin (PRF) to reducedpostoperative complications following lower third molar surgery included 6 RCTs.
The findings are consistent to other reviews finding that PRF derivative may lead to improvements in postoperative outcomes from third molar surgery but the amount of evidence is limited.

[read the full story...]