Platelet Rich Fibrin as a biomaterial in oral surgery

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This blog on a review of the efficacy of platelet rich fibrin (PRF) in oral surgery procedures was prepared by MSc Students from @UClanDentistry during a workshop with the @TheDentalElf. The review includes 30 small studies of limited quality more high quality studies are needed to assess effectiveness.

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Chlorhexidine mouthwash after periodontal or implant surgery

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This review of the benefits of chlorhexidine rinsing after periodontal or implant surgery included 11 small RCTs which provide very low quality evidence of a benefit.

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Palatal canines: open or closed surgical approaches?

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Two surgical approaches ( open and closed) for palatally displaced canines were compared in this multi-centre RCT. No differences in operating time was seen between the two approaches but those in the open group had more pain.

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Articaine or Lidocaine for third molar removal?

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This review of anaesthetic efficiency of articaine for lower third molar extraction included 9 RCTs ( 493 patients -770 lower molars). The findings suggest that 4% articaine with 1:100,000 epinephrine possesses superior anaesthetic efficiency relative to lidocaine.

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Bone augmentation in atrophic mandibles; autogenous bone or biomaterial?

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This review of bone augmentation with biomaterials or autogenous bone in the posterior mandible outcomes included 4 small split-mouth studies demonstrating similar were outcomes with both materials.

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Third molars: Regenerative techniques for preventing periodontal defects

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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.

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Autotransplantation of teeth with incomplete root formation have good success rates

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This review of success and survival rates and complications of autotransplantation of teeth with incomplete root formation included 32 observational studies only 5 of which were considered to be of high quality. Good success rates were noted but findings should be interpreted cautiously

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Oral anticoagulant therapy: Preventing bleeding in patients having dental extractions

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This Cochrane review of antifibrinolytic agents for preventing bleeding in people on oral anticoagulants undergoing dental extractions or minor oral surgery included 4 RCTs. Topical tranexamic acid was effective in reducing post-operative bleeding following dental procedures.

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Canine tooth transplantation

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This review of canine autotransplantation included 6 low quality studies are suggests good survival although both resorption and ankylosis increase after 5 years

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Third molar extraction – does platelet-rich fibrin improve outcomes?

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6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.

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