Dual antiplatelet therapy and post-operative bleeding following minor oral surgery

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This review of bleeding complications in patients on dual antiplatelet therapy compared to patients on single antiplatelet or no antiplatelet therapy for patients undergoing oral surgery included 16 studies but no randomised trials. Findings suggest that dual antiplatelet therapy should not be discontinued but the evidence is of low quality.

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Direct anticoagulant agents: management before invasive dental procedures

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This review of the evidence of bleeding events following invasive oral procedures in patients using direct anticoagulant agents (DOACs) identified 21 studies but no RCTs. The review found no important differences in bleeding events in patients who continued versus patients who discontinued DOAC therapy.

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COX-2 inhibitors for pain management after third molar removal

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing the efficacy of Cox-2 inhibitors with ibuprofen after third molar removal included 12 RCTs suggesting that COX-2 inhibotors and Ibuprofen provide similar pain relief at 6, 8, and 12 h after third molar removal.

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Actinic cheilitis: What is the best treatment?

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This review of treatments for actinic cheilitis included 29 mainly observational studies providing little evidence to identify the best treatment approaches.

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Dental implant placement: which antibiotic protocol?

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This review of the the effectiveness of different antibiotic protocols to prevent early dental implant failure includes 9 RCTs showing that antibiotics were protective against early implant failures.

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Antibiotic prophylaxis for dental implants in healthy patients, is it necessary?

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This review of the efficacy of antibiotic prophylaxis in dental implant placement for prevention of post-operative infection included 10 RCTs analysis indicatingthat antibiotic prophylaxis may not be necessary in health patients.

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Platelet Rich Fibrin as a biomaterial in oral surgery

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This blog on a review of the efficacy of platelet rich fibrin (PRF) in oral surgery procedures was prepared by MSc Students from @UClanDentistry during a workshop with the @TheDentalElf. The review includes 30 small studies of limited quality more high quality studies are needed to assess effectiveness.

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Chlorhexidine mouthwash after periodontal or implant surgery

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This review of the benefits of chlorhexidine rinsing after periodontal or implant surgery included 11 small RCTs which provide very low quality evidence of a benefit.

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Palatal canines: open or closed surgical approaches?

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Two surgical approaches ( open and closed) for palatally displaced canines were compared in this multi-centre RCT. No differences in operating time was seen between the two approaches but those in the open group had more pain.

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