Ketamine “shows promise” as an anti-suicidal ideation agent, but will this promise ever be realised?

sinitta-leunen-aFXiQMUi2zA-unsplash

Rosalind McAlpine and Karel Kieslich summarise a recent systematic review which focuses on the rapid anti-suicidal ideation effect of ketamine.

[read the full story...]

Exposure to air pollution increases mental health service use, according to new UK study

Road,Street,Sign,For,Switch,Off,Engine,To,Reduce,Emissions

Wajeeha Raza and Peter Coventry review a retrospective cohort study exploring the association between air pollution exposure and mental health service use among individuals with first presentations of psychotic and mood disorders.

[read the full story...]

Lamotrigine in the maintenance treatment of bipolar disorder

Lamotrigine, an anticonvulsant drug, is licensed in the United States for the maintenance treatment of bipolar I disorder and in the UK to prevent depressive episodes in bipolar disorder. Hashimoto and colleagues (2021) performed a Cochrane Intervention Review to explore whether lamotrigine is effective and safe compared to the most established maintenance treatment, lithium, and placebo.

Michael Ostacher critically appraises and summarises a recent Cochrane systematic review, which presents the latest best evidence on the efficacy of lamotrigine in the maintenance treatment of bipolar disorder.

[read the full story...]

Mental health: at what cost?

todd-trapani-EHrEGnep2K4-unsplash

In their debut Mental Elf blog, Martin Knapp and Gloria Wong summarise a systematic review of cost-of-illness studies, which explores the distribution of the costs between different mental health and neurodevelopmental conditions.

[read the full story...]

Home treatment by crisis resolution teams can prevent hospital admission, according to Swiss research

Featured

Emmeline Lagunes Cordoba and Magdalena Skowronska review a recent Swiss RCT, which found that crisis resolution teams led to fewer hospital days per patient, but did not prevent hospital admission entirely.

[read the full story...]

Homelessness and mental illness in children and young people

shutterstock_177426335

This study explores the prevalence of psychiatric disorder and comorbidity among a UK sample of young people with experience of homelessness. It finds an extremely high prevalence of mental illness, combined with low levels of mental health service use.

[read the full story...]

The side effects of lithium: new systematic review provides toxicity profile

shutterstock_185880

Lithium is a medicine that has been used for over 50 years to treat depression and bipolar disorder. It comes in two forms that are used clinically: lithium carbonate and lithium citrate. A certain level of the drug is needed in the blood stream for it to be effective, but if the level rises too [read the full story…]

Meta analysis reveals different structural brain abnormalities in depression and bipolar disorder

shutterstock_9224149 mri scan

It has long been documented that there are clinical differences between depression and bipolar disorder, but to date there has been no reliable study that shows differences in structural brain abnormalities in the two disorders. A research team from the Institute of Psychiatry in London have published a meta analysis that investigates structural brain changes in [read the full story…]