Reminiscence therapy for people living with dementia: Cochrane review is inconclusive

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Liz Collier and Solomon Towuru summarise the recently updated Cochrane systematic review on reminiscence therapy for dementia, which includes evidence showing that reminiscence therapy may improve quality of life, cognition, communication and possibly mood in people with dementia in some circumstances, although all the benefits were small.

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Mandibular advancement devices in obstructive sleep apnoea: side effects

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21 studies mainly retrospective studies were included in this review of the dental and skeletal effects of mandibular advancement devices in treatment of obstructive sleep apnoea. while the findings suggest a number of potential side effects the quality of the available evidence in low.

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Antidepressant withdrawal: reviewing the paper behind the headlines

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Joseph Hayes and Sameer Jauhar set the record straight on antidepressant withdrawal. They show how the recent review by Davies and Read is seriously flawed and does not accurately portray the data. They conclude that we urgently need clearer evidence on the incidence, severity and duration of any symptoms related to antidepressant withdrawal.

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Orthodontic treatment with fixed appliance had no impact on clinical attachment level

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This review of the impact of fixed appliance orthodontic treatment on clinical attachment levels included 9 small prospective studies finding no no clinically relevant detrimental effect. However the overall level of evidence is low to very low.

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What causes emotional blunting in people taking antidepressants? Results from a survey

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Linda Gask looks at a recent survey of people with depression that explores their experiences of emotional blunting. The research finds that nearly half of depressed patients on antidepressants report significant emotional blunting, but it’s impossible to say whether this is caused by their medication or the depression itself.

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Fissure sealants effective in preventing caries in children and adolescents

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38 trials were included in this updated Cochrane review of the effect of fissure sealants on occlusal caries. The data show a reduction in caries of between 11-51% at 24months compared to no sealant. The benefit was also maintained at longer-term follow up.

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Orthodontic retainers: impact on periodontal health

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While 24 studies were included in this review of the impact of orthodontic retainers on periodontal health there was a lack of high quality evidence to support any particular retainer on this or a range of other parameters. More well-designed and long terms studies are required.

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Psychotropic medication in pregnancy: new evidence may help achieve a safe balance

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Joanne Wallace considers a recent health technology assessment on the risks and benefits of psychotropic medication in pregnancy, which supports previous associations between valproate and adverse child outcomes.

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Dental local anaesthesia and ophthalmic side effects

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65 case reports and 1 case series were included in this reviews of the ophthalmic side effects from dental local anaesthesia. 92 % were transitory the remainder permanent. 25% of the transitory side effects took up to 6 hours to resolve.

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