What causes emotional blunting in people taking antidepressants? Results from a survey


Linda Gask looks at a recent survey of people with depression that explores their experiences of emotional blunting. The research finds that nearly half of depressed patients on antidepressants report significant emotional blunting, but it’s impossible to say whether this is caused by their medication or the depression itself.

[read the full story...]

Fissure sealants effective in preventing caries in children and adolescents

Fissure sealant

38 trials were included in this updated Cochrane review of the effect of fissure sealants on occlusal caries. The data show a reduction in caries of between 11-51% at 24months compared to no sealant. The benefit was also maintained at longer-term follow up.

[read the full story...]

Orthodontic retainers: impact on periodontal health


While 24 studies were included in this review of the impact of orthodontic retainers on periodontal health there was a lack of high quality evidence to support any particular retainer on this or a range of other parameters. More well-designed and long terms studies are required.

[read the full story...]

Psychotropic medication in pregnancy: new evidence may help achieve a safe balance

pregnant with ipad

Joanne Wallace considers a recent health technology assessment on the risks and benefits of psychotropic medication in pregnancy, which supports previous associations between valproate and adverse child outcomes.

[read the full story...]

Dental local anaesthesia and ophthalmic side effects


65 case reports and 1 case series were included in this reviews of the ophthalmic side effects from dental local anaesthesia. 92 % were transitory the remainder permanent. 25% of the transitory side effects took up to 6 hours to resolve.

[read the full story...]

Few adverse events with single dose oral analgesics for acute postoperative pain

This overview of adverse event rates associated with single dose oral analgesics includes data from 39 Cochrane reviews, and provides evidence that adverse events rates are generally similar with active drug and placebo.

[read the full story...]

Tooth whitening at home–strips or gel?

shutterstock_73004329-tooth whitening

This review compared tooth whitening strips against 10% carbamide peroxide gel. Only 9 low quality studies were available and while meta-analysis found no difference between the interventions, the authors did not consider that strips were a substitute for gel.

[read the full story...]

Air polishing- glycine powder has less potential for harm suggests review


This review included 17 studies the majority (12) of which were in vitro; and all at risk of bias to greater or lesser extent. The results suggest that glycine powder air polishing had less potential for harm of oral hard and soft tissues than sodium bicarbonate powders.

[read the full story...]

Evidence on the adverse effects of interproximal dental stripping is limited


Interproximal dental stripping or interproximal enamel reduction (IER) was originally suggested back in the 1940s as a method of gaining space in the lower incisor region.  The aim of this review was to investigate the enamel roughness resulting from IER as well as the cariogenicity of IER in orthodontic patients. The databases, PubMed, Scopus, The [read the full story…]