COX-2 inhibitors for pain management after third molar removal

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing the efficacy of Cox-2 inhibitors with ibuprofen after third molar removal included 12 RCTs suggesting that COX-2 inhibotors and Ibuprofen provide similar pain relief at 6, 8, and 12 h after third molar removal.

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Third molars: Distal caries development in adjacent second molars

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This review of the prevalence of distal surface caries in second permanent molars associated with retained third molars included 11 mainly retrospective observational studies findins a pooled prevalence of 23% (95% CI; 2% to 44%).

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Articaine or Lidocaine for third molar removal?

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This review of anaesthetic efficiency of articaine for lower third molar extraction included 9 RCTs ( 493 patients -770 lower molars). The findings suggest that 4% articaine with 1:100,000 epinephrine possesses superior anaesthetic efficiency relative to lidocaine.

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Third molars: Regenerative techniques for preventing periodontal defects

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This review of the effectiveness of regenerative periodontal treatment for preventing periodontal defects following third molar surgery included 21 RCTs and suggested that these approaches were effective. However a majority of the included studies were at high risk of bias so the findings should be interpreted cautiously.

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Third molar surgery: Steroids had a beneficial effect on pain, swelling and trismus

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This review of effectiveness of corticosteroids in the post-operative control of pain, swelling and trismus after third molar surgery included 17 RCTs suggesting that corticosteroid use had beneficial effects on pain swelling and trismus.

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Mandibular angle fractures – Do third molars have an influence?

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16 observational studies were included in this review of the association between the presence of a lower third molar and the occurrence of a mandibular angle fracture in adults. The findings suggest that the odds of fracture are 3.16 (95%CI; 2.2- 4.54) higher in the presence of third molars

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Third molar extraction – does platelet-rich fibrin improve outcomes?

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6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.

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Mandibular fractures: the influence of third molars

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This review of the effect of presences of third molars on mandibular fractures includes 35 observational studies. The findings suggest that the presence of third molars increases the change of mandibular angle fractures.

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Orthodontic extractions and third molar angulation

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This review of the effect of orthodontic extractions on the angulation of third molars included only 14 retrospective studies. This provides very low quality evidence of any effect

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