Does CBT really outperform other treatments for depression in primary care settings? A recent systematic review suggests patients may have more options than we think.
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A new meta-analysis from Toutountzidis and colleagues finds trauma-focused therapies meaningfully reduce delusions in psychosis, but offer limited benefit for hallucinations. Younger people gain most.
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Psychedelic therapy looks impressive in trials, but when you account for the placebo effect, how does it really compare to antidepressants?
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If your friend is struggling with suicidal thoughts, are you at greater risk? A meta-analysis of over 1 million people explores the evidence.
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Systematic review of 54 RCTs found limited evidence for cannabinoids treating mental health conditions. Most robust findings for cannabis use disorder, but overall quality low.
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Umbrella review of global prison populations finds 40% with antisocial personality disorder, 39% with drug use disorder, 24% with alcohol use disorder, 18% with hepatitis C, and 11% with major depression. Healthcare provision inadequate.
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Mental health service users face higher sexual victimisation rates than the general population: 13% in the past year for women, 3% for men, across all service settings.
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Systematic review of 60 studies found personality disorders affect 5.2% in high-income countries, associated with elevated mortality, yet excluded from global disease burden estimates.
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Meta-analysis of 46 studies found mindfulness and acceptance programmes significantly reduced OCD symptoms, performing as well as CBT but with more research needed on long-term effects.
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Decades of disappointing anti-inflammatory trials for depression may have failed because they weren’t targeting the right patients. New meta-analysis shows promising results when they do.
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