Adolescent cannabis use and risk of depression and suicide

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Benjamin Janaway blogs about a major data analysis that links adolescent cannabis use with increased risk of depression and suicide. He considers the opportunities for early recognition of cannabis use and public intervention.

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Higher doses of antidepressants “not optimal”, according to new review

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Jonathon Tomlinson considers his options as a GP supporting people with depression and complex needs, after reading a new systematic review and dose-response meta-analysis, which suggests that higher doses of antidepressants bring maximum side effects with only marginal gains.

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New genes implicated in Alzheimer’s disease #LetsTalkMentalHealthII

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Byron Creese writes a #LetsTalkMentalHealthII blog about a recent genome-wide meta-analysis which identifies new loci and functional pathways influencing Alzheimer’s disease risk.

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Compulsory detention under the Mental Health Act: significantly more likely if you come from a BAME or migrant group

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Ian Cummins explores a recent international systematic review and meta-analysis, which highlights ethnic variations in compulsory detention under the Mental Health Act.

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Suicide risk assessment among psychiatric inpatients: pessimism around predictive power

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Alex Langford appraises a systematic review that looks at high-risk categories for suicide risk assessment among psychiatric inpatients.

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Rates of psychotic disorders: huge variability and important risk factors

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Emma O’Neill summarises a systematic review and meta-analysis of the incidence of psychotic disorders, which looks at the distribution of rates and the influence of gender, urbanicity, immigration and socio-economic level.

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Is self-management ready for the mental health mainstream?

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Josefien Breedvelt and Peter Coventry explore a new systematic review and meta-analysis of self-management interventions for people with severe mental illness.

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What’s the relationship between adolescent depression and adult depression?

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Katie Finning writes her debut elf blog on a recent systematic review which looks at adult mental health outcomes of adolescent depression; including depression, anxiety and suicidality in adults.

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Psychotherapy for adult depression: is it as good as it’s cracked up to be?

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Ellie Gant summarises a meta-analysis that asks: Was Eysenck right after all? A reassessment of the effects of psychotherapy for adult depression. The paper suggests that we seriously overestimate the benefits of psychotherapy by including biased trials in meta-analyses, and that there’s insufficient reliable research to be certain about the effectiveness of problem-solving therapy, interpersonal psychotherapy and behavioural activation.

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Can interventions help to improve social functioning in youth at risk of psychosis?

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Carla McEnery summarises a systematic review and meta-analysis of interventions and social functioning in youth at risk of psychosis.

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