Intraosseous injection or inferior alveolar nerve block for third molar surgery?

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This review comparing the anaesthetic efficacy of intraosseous injection(IO) and conventional inferior alveolar nerve block (INAB) in mandibular third molar surgery included 4 small RCTs. The findings suggest no significant difference between IO and INAB techniques.

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Endodontic sealers and the outcome of endodontically treated permanent teeth

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This review comparig the outcomes of silicate-based sealers with resin-based sealers in non-surgical root treatments included 12 studies (9 RCTs). The findings suggest no difference between the two sealant types in the short term.

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The North American Opioid Crisis: how it came about and how to manage it

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Rob Poole explores the recently published Stanford-Lancet Commission report on the North American Opioid Crisis, which aims to understand the opioid crisis, propose solutions to the crisis in the USA and Canada, and attempt to stop its spread internationally.

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Cranio-mandibular manual therapy for temporomandibular disorders

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This review of cranio-mandibular manual therapy (CMMT) on pain and maximum mouth opening in people with temporomandibular disorders included 6 RCTs. While the available evidence supports the use of CMMT it is of very low quality so should be interpreted cautiously.

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Anaesthetic techniques for mandibular posterior teeth with symptomatic irreversible pulpitis

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This review of the most effective method of anaesthesia for mandibular posterior teeth with symptomatic irreversible pulpitis included 22 RCTs. The findings suggest that buccal infiltraion and inferior alveolar nerve block ,Vazirani-Akinosi nerve block and introsseus injections performed better but the evidence was only of low to very low certainty.

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Platelet-rich fibrin to reduce post-operative complications of lower third molar removal

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This review of platelet-rich fibrin (PRF) to reducedpostoperative complications following lower third molar surgery included 6 RCTs.
The findings are consistent to other reviews finding that PRF derivative may lead to improvements in postoperative outcomes from third molar surgery but the amount of evidence is limited.

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Platelet-rich fibrin and third molar post extraction problems

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This review of the effectiveness of leukocyte-and platelet-rich fibrin (L-PRF) and advanced-platelet-rich fibrin (A-PRF) in mandibular third molar extraction included 10 RCTs. While the findings suggest some benefits the studies are small and limited in number so the findings should be interpreted cautiously.

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Occlusal reduction and post-endodontic pain

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This review analysing the influence of occlusal reduction on postoperative pain levels after endodontic treatment includes 12 RCTs. The findings suggests no difference was seen in post-treatment pain levels after occlusal reduction.

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Topical anaesthesia: Does it reduce pain perception of local anaesthetic injections?

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This review of the effectiveness of topical anaesthesia in in reducing pain during local anaesthetic injections for dental procedures included 22 RCTs. Statistically significant differences were seen during needle puncture with topical anaesthetic use in the maxilla and palate but not the mandible.

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Third molar extraction– effect of preoperative oral corticosteroids on pain, swelling and trismus

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Four RCTs involving a total of 212 patients were included in this review of a single pre-operative dose of oral corticosteroids in reducing pain,swelling & trismus after surgical removal of lower third molars. While the findings suggested there was little benefit to the patients none of the studies were small and none of them were at low risk of bias.

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