This review of the most effective method of anaesthesia for mandibular posterior teeth with symptomatic irreversible pulpitis included 22 RCTs. The findings suggest that buccal infiltraion and inferior alveolar nerve block ,Vazirani-Akinosi nerve block and introsseus injections performed better but the evidence was only of low to very low certainty.
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This review of platelet-rich fibrin (PRF) to reducedpostoperative complications following lower third molar surgery included 6 RCTs.
The findings are consistent to other reviews finding that PRF derivative may lead to improvements in postoperative outcomes from third molar surgery but the amount of evidence is limited.
This review of the effectiveness of leukocyte-and platelet-rich fibrin (L-PRF) and advanced-platelet-rich fibrin (A-PRF) in mandibular third molar extraction included 10 RCTs. While the findings suggest some benefits the studies are small and limited in number so the findings should be interpreted cautiously.
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This review analysing the influence of occlusal reduction on postoperative pain levels after endodontic treatment includes 12 RCTs. The findings suggests no difference was seen in post-treatment pain levels after occlusal reduction.
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This review of the effectiveness of topical anaesthesia in in reducing pain during local anaesthetic injections for dental procedures included 22 RCTs. Statistically significant differences were seen during needle puncture with topical anaesthetic use in the maxilla and palate but not the mandible.
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Four RCTs involving a total of 212 patients were included in this review of a single pre-operative dose of oral corticosteroids in reducing pain,swelling & trismus after surgical removal of lower third molars. While the findings suggested there was little benefit to the patients none of the studies were small and none of them were at low risk of bias.
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This Cochrane review of the effectiveness of lasers in the treatment of dentine hypersensitivity included 23 RCTs. The findings suggest that lasers may reduce pain intensity at short, medium, or long term when compared to placebo/no treatment. However the evidence is limited and of low to very low certainty.
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This review of postoperative discomfort, operative time, and wound healing in the short-term follow-up following surgical extraction of lower third molars with lingual- or buccal-based flaps included 7 RCTs. The quality of the included studies was limited and few differences were seen between the type of flaps.
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This review the efficacy of stabilisation appliances in the management of painful temporomandibular disorders (TMDs) included 24 RCTs. The findings suggest they have an efficacy beyond the placebo effect however the evidence of low to very low certainty.
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This review of the efficacy of 1.8 and 3.6 mL of the same anaesthetic solution for inferior alveolar nerve blocks (IANBs) for treating mandibular teeth with irreversible pulpitis included 4 RCTs (280 teeth). The findings show arger volumes of local anaesthetic solutions significantly increase the success rate of IANBs.
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