Buffering local anaesthetics to reduce dental injection pain?

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14 RCTs were included in this review of the effect of buffering local anaesthetics in reducing infiltration pain and anaesthesia onset time in dentistry. While slight reductions in onset time was seen in inflamed tissues and for IAN block these were not considered to be clinically significant. However the overall quality of the evidence was low.

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Orthodontic pain: Is low level laser therapy effective?


20 RCTs were included in this review of low level laser therapy (LLLT) for orthodontic pain. While the findings suggest a benefit a majority of the studies were at high risk of bias so the findings should be interpreted cautiously.

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Third molar extraction – does platelet-rich fibrin improve outcomes?


6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.

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Root canal obturation using core-carrier techniques


19 studies were included in this review of core-carrier obturation techniques in endodontic treatment. Success rates was 83%(95CI; 69-91%) with 24% suffering postoperative pain and 31% having overfilling.

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Pain during orthodontic treatment –pharmacological treatments

iStock_000002551343XSmall colourful braces on teeth

This Cochrane review of drug interventions for pain during orthodontic treatment including 32 RCTs find that analgesics were effective in reducing pain. However, low quality evidence did not show a difference in effectiveness between systemic NSAIDs compared with paracetamol, or topical NSAIDs compared with local anaesthetic.

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Palatally displaced canines: open or closed surgical exposure?

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This updated Cochrane review comparing open v closed surgical approaches for palatally displaced canines includes 3 studies involving 146 patients with the available evidence suggesting that neither surgical technique for exposing canine teeth is superior.

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Endodontic pain can be managed with non-steroidal anti-inflammatory drugs


This review of the use of non-steroidal anti-inflammatory drugs (NSAIDs) for the management of post endodontic pain demonstrates that they do help to manage the pain.

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Post-endodontic pain: is it lower with rotary or reciprocating instruments?


This review of the effect of rotary or reciprocating instruments on post-endodontic pain included 3 RCTs involving 1317 patients. There is limited evidence of any clear difference between the two techniques.

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Temporomandibular lavage for temporomandibular disorders


This review of TMJ lavage for temporomandibular disorders only included 5 small RCTs a majority of which were at high risk of bias. While the findings suggest a benefit from lavage this should be interpreted cautiously because of the limited quality of the available evidence.

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Anxiety and pain during dental treatment


35 studies investigating 47 clinical groups were included in this review of the association between dental anxiety and pain during dental treatment. The findings suggest a consistent impact on pain through the entire period of dental treatment.

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