This review evaluating the effectiveness of desensitising toothpastes included 53 RCTs. Most agents with the exception of those containing strontium or amorphous calcium phosphate were effective in relieving dentine hypersensitivity compared with negative controls.
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This review of dexamethasone for controlling pain following endodontic treatment included 5 relatively small RCTs . The findings suggest statistically significant reduction of pain in patients receiving dexamethasone at 8,12, and 24 hours.
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This review of the efficacy of corticosteroids on postoperative endodontic pain. found that patients receiving corticosteroids reported significantly lower pain scores at 6, 12 and 24hrs postoperatively.
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This review of the effectiveness of chemomechanical caries removal in primary teeth identified 15 studies with 10 contributing to the quantitative analysis. The findings suggest this approach is less painful but takes longer than traditional approaches.
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This review comparing articaine and lidocaine for local anesthesia use in children only identified 6 low quality studies. Little difference was seen between the two agents.
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14 RCTs were included in this review of the effect of buffering local anaesthetics in reducing infiltration pain and anaesthesia onset time in dentistry. While slight reductions in onset time was seen in inflamed tissues and for IAN block these were not considered to be clinically significant. However the overall quality of the evidence was low.
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20 RCTs were included in this review of low level laser therapy (LLLT) for orthodontic pain. While the findings suggest a benefit a majority of the studies were at high risk of bias so the findings should be interpreted cautiously.
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6 studies were identified for this review of platelet-rich fibrin to improve outcomes after third molar extraction. The studies were small with contradictory findings so further high quality studies are needed.
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19 studies were included in this review of core-carrier obturation techniques in endodontic treatment. Success rates was 83%(95CI; 69-91%) with 24% suffering postoperative pain and 31% having overfilling.
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This Cochrane review of drug interventions for pain during orthodontic treatment including 32 RCTs find that analgesics were effective in reducing pain. However, low quality evidence did not show a difference in effectiveness between systemic NSAIDs compared with paracetamol, or topical NSAIDs compared with local anaesthetic.
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