This review of the effectiveness of leukocyte-and platelet-rich fibrin (L-PRF) and advanced-platelet-rich fibrin (A-PRF) in mandibular third molar extraction included 10 RCTs. While the findings suggest some benefits the studies are small and limited in number so the findings should be interpreted cautiously.
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Four RCTs involving a total of 212 patients were included in this review of a single pre-operative dose of oral corticosteroids in reducing pain,swelling & trismus after surgical removal of lower third molars. While the findings suggested there was little benefit to the patients none of the studies were small and none of them were at low risk of bias.
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This review of postoperative discomfort, operative time, and wound healing in the short-term follow-up following surgical extraction of lower third molars with lingual- or buccal-based flaps included 7 RCTs. The quality of the included studies was limited and few differences were seen between the type of flaps.
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This review of whether low-level laser therapy (LLLT) is effective in reducing postoperative morbidity in patients undergoing surgical removal of mandibular third molars included 17 RCTs. The findings suggest a reduction in post-operative swelling but not pain or trismus.
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This Cochrane review update of the effect of systemic antibiotic prophylaxis on the prevention of infectious complications following tooth extractions included 23 studies. There was very-low certainty evidence that prophylactic antibiotics may reduce the risk of infection and dry socket following third molar extraction compared to placebo.
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This review of the risk of hyperaesthesia with articaine compared with other local anaesthetics in lower alveolar nerve block for lower third molar removal included 13 studies.The findings suggest that the use of articaine does not increase the risk of hyperaesthesia.
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This review of the effectiveness of different anaesthetic solutions for pain control immediately after the extraction of lower third molars included 45 studies.13 studies were included in a network meta-analys whch suggested 5% bupivacaine reduces pain in patients during and immediately after the removal of lower third molars.
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Our most popular blogs from January, February and March 2020 were about the FiCTION trial, local anaesthesia and factors associated with third molar surgical difficulty.
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This review comparing the efficacy and safety of currently available local anaesthetics for lower third molar extraction included 24 RCTs. The findings suggest that 4% articaine was the most effective and lidocaine the safest.
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This Cochrane review upate compares the relative benefits and risks of different techniques for surgical removal of mandibular wisdom teeth. While the review includes 25 new trials the quality of the studies was variable with many having biases that could have influenced the findings so no meaningful conclusions could be drawn.
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