A single dose of tocilizumab cleared inflammation in depressed patients, but did it ease their symptoms? A proof-of-concept RCT with cautious promise.
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Depression, anxiety, and suicidality are higher among LGBTQ+ workers, especially in hostile or unsupportive workplaces. But are research and policy keeping up? This new review sets out the case for change.
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GLP1 drugs are already used to treat diabetes and support weight loss, but do they have any impact on mental health? This new meta-analysis looks at the evidence from 80 clinical trials.
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Fionnuala Rogers discusses a study on the role of white matter microstructure in depression-related cognitive dysfunction, which highlights the importance of viewing major depressive disorder not only as a mood disorder, but as a condition with significant neurocognitive implications.
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Julian Mutz discusses the results of a new 10-week RCT assessing home-based brain stimulation for depression, which suggests that tDCS may be a safe, acceptable and efficacious treatment for moderate depression.
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Sofiia Kornatska considers a recent systematic review on effective and feasible psychological interventions for populations under ongoing threats; including terrorist attacks, shootings, fire, physical and psychological abuse, political and armed violence, and ongoing intimate partner violence.
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Dona Matthews summarises a recent trial which suggests that Acceptance and Commitment Therapy can maintain or improve quality of life for people with early stage motor neuron disease.
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We all had an extra hour in bed this weekend, but what impact does shifting the clocks back and forward each year have on our life satisfaction?
Melanie De Lange summarises a recent study on the welfare effects of time reallocation, which uses Daylight Saving Time evidence from Germany.
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In her debut blog, Ana Julia Ferreira summarises a randomised controlled trial investigating the effectiveness of a digital self-help intervention for improving bulimic-spectrum disorder symptomatology while on a treatment waiting list.
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A team of experts from the Global NIHR Centre for IMPACT consider the findings of a recent review, which looks at the effectiveness and implementation of psychological interventions for depression in people with non-communicable diseases in Pakistan and Bangladesh.
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