Nocebo response in third molar analgesic trials

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This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.

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Endodontic sealers and the outcome of endodontically treated permanent teeth

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This review comparig the outcomes of silicate-based sealers with resin-based sealers in non-surgical root treatments included 12 studies (9 RCTs). The findings suggest no difference between the two sealant types in the short term.

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Ibuprofen prior to lower third molar removal

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This review of the effect of pre-emptive ibuprofen on post-operative pain after lower third molar surgery included 5 RCTs. Only one of the included studies was at low risk of bias so there is insufficient evidence to support the routine use of pre-emptive ibuprofen to reduce post-operative pain after lower third molar removal

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Third molar surgery – Er:Yag lasers and post-operative problems

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This review of the effectiveness of Er:YAG lasers in reducing pain, oedema and trismus compared to rotary instruments for the removal of impacted lower third molars included 6 small studies only one of which was at low risk of bias. The findings suggest a reduction in swelling and a small reduction in pain however the findings should be viewed cautiously because of the limited amount and quality of the evidence.

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Post endodontic pain: Is it affected by irrigation technique?

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This review of whether ultrasonic irrigation results in less postoperative root canal treatment pain than conventional irrigation included 6 RCTs. The suggests less pain with ultrasonic irrigation for the first 48 hours but no difference at 72 hours.

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Third molar surgery: Does low-level laser therapy reduce post-operative morbidity?

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This review of whether low-level laser therapy (LLLT) is effective in reducing postoperative morbidity in patients undergoing surgical removal of mandibular third molars included 17 RCTs. The findings suggest a reduction in post-operative swelling but not pain or trismus.

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Post-operative endodontic symptoms: Are they improved by prophylactic antibiotics?

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This review of the efficacy of prophylactic oral antibiotics in the management of post-operative endodontic symptoms included 10 RCTs. The findings and show that there is no superiority in using adjunctive antibiotics for the prevention of post-operative endodontic symptoms.

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Tooth extraction: Do antibiotics prevent complications?

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This Cochrane review update of the effect of systemic antibiotic prophylaxis on the prevention of infectious complications following tooth extractions included 23 studies. There was very-low certainty evidence that prophylactic antibiotics may reduce the risk of infection and dry socket following third molar extraction compared to placebo.

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Endodontic retreatment:Post-operative pain in single or multiple visits

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This review assessing the postoperative pain after non- surgical endodontic retreatment in a one visit compared to multiple visits included 4 RCTs. The availabe evidence suggests little difference between teh two approaches.

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Third molar extractions: Which anaesthetic solution for the best pain control?

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This review of the effectiveness of different anaesthetic solutions for pain control immediately after the extraction of lower third molars included 45 studies.13 studies were included in a network meta-analys whch suggested 5% bupivacaine reduces pain in patients during and immediately after the removal of lower third molars.

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