This randomised controlled trial of a single, preoperative oral dose of prednisolone on post-endodontic pain involved 400 patients demonstrating a significant reduction in pain at 6,12 and 24 hours.
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This small but well conducted RCT compares the effectiveness of MTA and calcium hydroxide for direct pulp capping material in adult molars with carious pulpal exposure finding better performance for MTA at 3 years.
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This review of the use of non-steroidal anti-inflammatory drugs (NSAIDs) for the management of post endodontic pain demonstrates that they do help to manage the pain.
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The review of NSAIDs for endodontic postoperative pain suggests that NSAIDs are effective. A combination of ibuprofen 600 mg and acetaminophen 1000 mg and Ibuprofen 600 mg were both effective. More studies are need to assess teh most effective NSAIDs dosages and does intervals.
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This Cochrane review update included 25 RCTs comparing single verses multiple root canal treatment approaches. They found no evidence to suggest that one treatment regimen is better than the other.
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This Cochrane review found 5 RCTs of pre-op analgesics prior to dental treatment for children under local anaesthetic. The evidence as insufficient to determine a benefit but there may be a benefit prior to orthodontic band placement. Further high quality studies are needed.
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This review of piezoelectric surgery for third molar removal included 9 studies, 6 of which were RCTs. The findings suggest that outcomes were better for piezoelectric surgery but these findings should be viewed cautiously.
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This review included 8 RCTs involving a total of 476 patients and found that submucosal dexamethasone reduced postoperative pain and swelling. Although only one of the studies was at low risk of bias and there was a possibility of publication bias, the findings should be considered with caution.
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5 studies were included in this review of hilotherapy. While the studies suggest that hilotherapy might provide patients with a significant reduction in postoperative facial pain and oedema, the quality of the studies is low.
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This Cochrane review included 14 trials of variable quality that could not be combined due to variation in local anaesthetic delivery and outcome measures. So the results from individual studies for pain, bleeding and other adverse effects are uncertain.
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