Burning mouth syndrome treatments – network meta-analysis

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This review of all treatments for the relief of pain associated with burning mouth syndrome (BMS) as compared with no intervention or placebo included 44 RCTs. There was moderate certainty evidence that clonazepam is likely to reduce the pain of BMS compared with placebo.

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Youth mental health interventions: umbrella review presents efficacy and acceptability data

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In his debut blog, Nick Meader tackles a huge umbrella review of youth mental health interventions, which presents the efficacy and acceptability of 72 different approaches to help children and young people.

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Treating PTSD in adults: EMDR and trauma-focused CBT still lead the way

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Nada Abou Seif summarises a network meta-analysis which finds that EMDR and trauma-focused CBT remain the most effective ways to treat adult PTSD.

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New evidence on treatments for symptoms of depression in dementia

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Andrew Sommerlad appraises a recent review on the efficacy of interventions for depression in people with dementia, which identified several non-drug treatments that can have a meaningful effect on depressive symptoms in dementia.

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Antidepressants for youth depression: Cochrane review confirms they should not be the first port of call

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Susannah Murphy summarises a new Cochrane review and network meta-analysis, which provides the best evidence to date about new generation antidepressants for depression in children and adolescents.

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Psychotherapies for suicide and self-harm in young people: join our tweet chat #YouthSuicidePrevention

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Laura Hemming summarises a review on the comparative efficacy and acceptability of psychotherapies for self-harm and suicide in young people, which highlights continued uncertainty in the field.

Join our tweet chat at 9am BST on Monday 24th May to discuss the future of #YouthSuicidePrevention research!

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Chronic periodontitis: Efficacy of adjunctive antimicrobials

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review of the efficacy of antimicrobials adjunctive to scaling and root planing (SRP) in the treatment of chronic periodontitis. 21 RCTs were included with the findings showing that amoxicillin and metronidazole had the largest statistical benefit. Whether this benefit is a clinically important benefit is a wider question.

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Psychological interventions effective for improving mental health and sleep following complex trauma

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In her debut blog, Delia Ciobotaru explores a network meta-analysis which finds that psychological treatments are effective in reducing PTSD symptoms experienced by people with complex trauma.

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Antidepressants and psychotherapy for adolescent depression: can they be compared? #ActiveIngredientsMH

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Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.

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CBT delivery formats for adult depression: group, telephone & guided self-help all as effective as individual therapy?

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Kinga Antal reviews a network meta-analysis which finds that individual, group, telephone and guided self-help CBT are all equally effective for treating depression in adults.

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