Psychological interventions effective for improving mental health and sleep following complex trauma

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In her debut blog, Delia Ciobotaru explores a network meta-analysis which finds that psychological treatments are effective in reducing PTSD symptoms experienced by people with complex trauma.

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Antidepressants and psychotherapy for adolescent depression: can they be compared? #ActiveIngredientsMH

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Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.

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CBT delivery formats for adult depression: group, telephone & guided self-help all as effective as individual therapy?

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Kinga Antal reviews a network meta-analysis which finds that individual, group, telephone and guided self-help CBT are all equally effective for treating depression in adults.

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Antipsychotics and metabolic function in people with schizophrenia

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Peter Haddad and Sami Ouanes review a network meta-analysis of the impact of antipsychotic drugs on metabolic function in people with schizophrenia.

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Medication for generalised anxiety disorder: new network meta-analysis

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A group of UCL Masters Students summarise a recent network meta-analysis of drug treatment for generalised anxiety disorder, which finds that Venlafaxine, Pregabalin, Escitalopram and Duloxetine are all viable alternatives to Benzodiazepines.

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Anti-plaque agents in toothpaste: Are they helpful in managing gingivitis?

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This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.

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Irreversible pulpitis: What is the most effective local anaesthetic for inferior alveolar nerve block?

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This review of the most effective anaesthetic solutions for inferior alveolar nerve blocks for mandibular teeth with irreversible pulpitis included 11 RCTs. The findings suggest that mepivacaine with epinephrine performed better than lidocaine with epinephrine but the number of trials is limited and the quality of evidence was very low to moderate.

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Medication for ADHD: what works for adults, adolescents and children

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Dean Connolly is impressed by a recent systematic review and network meta-analysis, which compares the efficacy and tolerability of medication for ADHD in children, young people and adults.

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Preventing psychosis: no one intervention is better than the rest

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A group of UCL Mental Health Masters students summarise a recent network meta-analysis that highlights a lack of evidence about specific interventions for preventing psychosis.

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Interdental cleaning aids

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This network meta-analysis of the comparative efficacy of interproximal oral hygiene aids included 22 RCTs and suggests that interdental brushes and water-jets ranked highest for the reduction of gingival bleeding. Although the quality of the available evidence is limited.

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