New genes implicated in Alzheimer’s disease #LetsTalkMentalHealthII

victor-vorontsov-528554-unsplash

Byron Creese writes a #LetsTalkMentalHealthII blog about a recent genome-wide meta-analysis which identifies new loci and functional pathways influencing Alzheimer’s disease risk.

[read the full story...]

The costs of care prior to institutionalisation among people living with Alzheimer’s disease

11180356596_99cd1af01c_o

The past few decades have seen a gradual shift of provision of services for older people from residential care to community-based care in the UK and other high-income countries. ‘Ageing in place’ is a widely accepted and supported discourse. In practice, receiving care at home enables older people to stay in a familiar environment, and [read the full story…]

Alcohol is the number one modifiable risk factor for dementia

huy-phan-587849-unsplash

Marie Crabbe looks at a recent retrospective cohort study in The Lancet Public Health which explores the contribution of alcohol use disorders to the burden of dementia in France.

[read the full story...]

Antidepressants for depression in Alzheimer’s Disease

mental-health-2211184_1280

The EQUATOR Publication School #EQPubSchool group summarise a systematic review and meta-analysis on the efficacy of antidepressants for depression in Alzheimer’s Disease, which finds no statistical difference between antidepressants and placebo.

[read the full story...]

Oral Health should have same priority as general health in care homes says NICE

Quality of life measures are one way of finding out how people are feeling about and experiencing their new life in a care home.

This new guidance from NICE focuses on improving and maintaining residents’ day-to-day oral healthcare, ensuring staff are properly trained to confidently look after the oral health needs of residents, and there is adequate access to dental services when needed

[read the full story...]

Long-term care placement for people with dementia

Mother and son

Clarissa Giebel reports on a systematic review and meta-analysis of factors predicting care placement of dementia sufferers into long-term care facilities.

[read the full story...]

Impact of functional alterations on quality of life in Alzheimer disease

An older woman out shopping

Clarissa Giebel analyses a qualitative study of how functional alterations impact quality of life in Alzheimer disease.

[read the full story...]

Commonly prescribed psychiatric drugs: do they work?

4932655275_7811863fe8_o

John Baker summarises a review of commonly prescribed medication that covers seven psychiatric drugs, including antidepressants, antipsychotics, benzodiazepines, amphetamines, methylphenidate and cholinesterase inhibitors.

[read the full story...]

Cognitive tests for dementia: MMSE, Mini-Cog and ACE-R

7158418_2215ef4a6e_b

Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.

[read the full story...]

Donepezil, nursing home placement and Alzheimer’s Disease

15482576136_fe7b9b5f42_k

Caroline Struthers reports on the findings of a follow-up paper of the DOMINO-AD trial, which compares Donepezil and Memantine for Moderate to Severe Alzheimer’s Disease, and looks at the effects these two drugs have on nursing home placement.

[read the full story...]