Results: 692

For: meta-analysis

Antidepressants can help adults with major depression

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André Tomlin reports on a new network meta-analysis that brings together the best available evidence comparing the efficacy and acceptability of 21 antidepressants for the acute treatment of adults with major depressive disorder.

This groundbreaking review of 522 trials is the largest ever meta-analysis in psychiatry, and finds that antidepressants are more effective than placebo for short-term treatment of acute depression in adults.

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Dental anxiety: Non-pharmacological treatment may be beneficial

Should we be paying more attention to anxiety in people with psychosis?

This review of non-pharmacological intervention to reduce mental distress, pain, and analgesic use in adults undergoing dental treatment included 29 RCTs. The findings suggest positive benefits for the interventions examined with no significant differences between the various interventions.

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Teacher burnout: can we prevent it, or is that the wrong question?

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As we prepare for our Youth Mental Health Question Time event in London this evening, Lucinda Powell considers a meta-analysis looking at the effectiveness of interventions aimed at reducing teacher burnout.

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Preventing anxiety with psychological and educational interventions

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Inês Pote publishes her debut elf blog about a recent systematic review on the effectiveness of psychological and/or educational interventions in the prevention of anxiety.

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Antiseptic oral sprays: Do they improve oral health?

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20 RCTs involving a total of 720 patients were included in this review of antiseptic oral sprays in the control of dental plaque and gingivitis. The findings suggest then can reduce plaque levels in the short term.

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Non-surgical periodontal therapy – which antibiotic regime?

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This review of amoxicillin & metronidazole as an adjunct to non-surgical periodontal treatment included 18 trials . A small benefit was seen with antibiotic use but no clinically meaningful difference between different doses or duration of amoxicillin-plus-metronidazole at 3 months post-treatment.

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Phytotherapy as an adjunct to nonsurgical periodontal treatment?

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7 small RCTs that majority of cross-over design were included in this review of phytotherapy as an adjunct to scaling and root planing for chronic periodontitis. While the findings suggest a benefit these should be viewed with caution until results from larger high quality studies are available.

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Orthodontic pain: Is low level laser therapy effective?

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20 RCTs were included in this review of low level laser therapy (LLLT) for orthodontic pain. While the findings suggest a benefit a majority of the studies were at high risk of bias so the findings should be interpreted cautiously.

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Silver diamine fluoride for caries in primary teeth

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This review of the effectiveness of silver diamine fluoride (SDF) in arresting caries included 11 studies with 4 contributing to a meta-analysis showing it to be more effective than other active agents and placebo.

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Fissure sealing using flowable composite

Fissure sealant

This review of fissure sealing using flowable composite included 11 studies and suggests retention rates at 1 year may be slightly better than resin-based sealants. However, the findings should be interpreted cautious as the confidence intervals are wide and quality of the studies is limited.

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