Results: 792

For: meta-analysis

Orthodontic bracket systems: Is adhesive precoating better than operator coated?

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This review assessing whether adhesive precoated orthodontic brackets are more efficient than operator-coated brackets included 5 RCTs find no differences in failure rate between the two systems.

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Reminiscence therapy for people living with dementia: Cochrane review is inconclusive

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Liz Collier and Solomon Towuru summarise the recently updated Cochrane systematic review on reminiscence therapy for dementia, which includes evidence showing that reminiscence therapy may improve quality of life, cognition, communication and possibly mood in people with dementia in some circumstances, although all the benefits were small.

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Mouth and throat cancer: evidence for best surgical approaches uncertain

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

12 RCTs were included in this Cochrane review update of surgical approches for the management of oral and pharyngeal cancer. The certaintly of the evidence was very low as there were limited numbers of studies for each comparison.

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Routine scale and polish for periodontal health

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Two UK primary care-based trials were included in this Cochrane review update of routine scale and polish. They provide high certainty evidence of litte or no difference between 6- & 12-monthly scale and polish for adult regular attenders without severe periodontitis.

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Medication for ADHD: what works for adults, adolescents and children

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Dean Connolly is impressed by a recent systematic review and network meta-analysis, which compares the efficacy and tolerability of medication for ADHD in children, young people and adults.

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Sedation for children undergoing dental treatment

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This Cochrane review update of the efficacy and relative efficacy of conscious sedation agents and dosages for behaviour management in paediatric dentistry includes 50RCTs providing some moderate-certainty evidence that oral midazolam is an effective sedative agent for children undergoing dental treatment.

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Youth suicide prevention research needs a shake-up: lives depend on it

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Pooky Knightsmith appraises a systematic review and meta-analysis entitled: “What Works in Youth Suicide Prevention?”. She is disappointed that the review does not answer the question it sets, but sees this as a call to action for better quality research to help save lives.

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Calcium hydroxide as lining for deep caries lesions?

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16 low quality RCTs were included in this review of the effect of calcium hydroxide lining on clinical success in treatment of deep carious lesions. 6 RCTs contributed to the meta-analysis suggesting no beneficial effect.

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Aloe vera for treatment of oral submucous fibrosis?

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This review effectiveness of aloe vera on alleviating the symptoms of oral submucous fibrosis included 6 RCTs . The findings suggest a possible benefit but 5 of the trials were at high risk of bias so the findings should be viewed cautiously.

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Periodontal infrabony defects: does autologous platelet concentrates (APC) improve surgical outcomes

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38 RCTs were included in this Cochrane review of the effects of autologous platelet concentrates (APC) used as an adjunct to periodontal surgery. Very low quality evidence was found for two approaches involving open flap debridement.

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