Results: 729

For: meta-analysis

CBT for anxiety: new meta-analysis confirms significant improvements to target symptoms

CBT plus taper is effective at reducing benzodiazepine use in the short term (3 months) but this effect is not sustained at 6 months.

Inês Pote summarises a recent meta-analysis of randomised placebo-controlled trials of cognitive behavioural therapy for anxiety and related disorders.

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Orthognathic surgery: Are perioperative steroids beneficial?

Bariatric surgery and marked weight loss is likely to improve knee complaints but there is a need for high quality studies

This review of perioperative systemic corticosteroids on clinically important outcomes in patients undergoing orthognathic surgery identified 8 small RCTs. A reduction in facial oedema was seen in those receiving systemic corticosteroids. However the quality of the studies is limited and there is lack of evidence on other outcomes or adverse effects.

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Suicide risk following childhood interpersonal violence

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Katrina Witt considers the findings of a meta-analysis of longitudinal studies, which looks at exposure to interpersonal violence in childhood, and the impact that it may have on risk of suicide in young people.

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Poorer cardiovascular screening, diagnosis and management if you have a mental illness

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Joanne Wallace summarises a systematic review that highlights disparities in the management of cardiovascular risk factors in people with mental illness.

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Glutaraldehyde or fluoride varnish for dentine hypersensitivity?

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This review of glutaraldehyde or fluoride varnish for dentine hypersensitivity included just 4 small RCTs . The findings suggest a benefit in favour of glutaraldehyde at 7 days but the short-term nature of the studies and their limited quality means these findings should be interpreted cautiously.

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Statins as an adjunct to periodontal treatment?

This well conducted Cochrane review found no evidence that statins

This review of the adjunctive effect of statins on mechanical periodontal therapy included 15 studies 12 of which were RCTs. The findings suggest a positive effect on probing pocket depth, clinical attachment level, and intrabony defects but the overall quality of evidence is considered to be low.

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Third wave CBT for psychosis: how reliable is current evidence?

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Keith Laws explores a recent meta-analysis of third wave CBT for psychosis, which suggests we need better evidence about the safety and efficacy of mindfulness, acceptance-based therapy, compassion-focused therapy and other third wave approaches.

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Post endodontic pain: Is it affected by type of instrumentation?

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17 studies, none of which were at low risk of bias, were included in this review of the effect of type of instrumentation on post endodontic pain. The findings suggest lower incidence and intensity of postoperative pain with rotary instruments compared to hand files.

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Dental adhesive systems: HEMA-free or HEMA-containing systems?

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22 RCTs were included in this review of the influence of the monomer HEMA in the formulation of dental adhesive systems suggests that HEMA-free adhesive systems do not have better clinical performance of the non-carious cervical lesion restorations than HEMA-containing systems.

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Anticoagulants and post-operative bleeding following oral surgery

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This review of the post oral surgery bleeding risk for patients on direct oral anticoagulants (DOACs) included 13 observational studies. The findings suggest a three-fold increase in bleeding for those patients on DOACs although the quality of the available evidence is limited.

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