Results: 817

For: meta-analysis

Platelet Rich Fibrin as a biomaterial in oral surgery

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This blog on a review of the efficacy of platelet rich fibrin (PRF) in oral surgery procedures was prepared by MSc Students from @UClanDentistry during a workshop with the @TheDentalElf. The review includes 30 small studies of limited quality more high quality studies are needed to assess effectiveness.

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Periodontitis and preterm birth

Antenatal mental health is a growing UK clinical and research priority, which affects all pregnant women

This review assessing the association between periodontitis and preterm birth included 31 studies with 20 contributing to a meta-analysis suggesting a significant positive association 2.01 (95%CI; 1.71 – 2.36).

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Cavity liners for resin-based composite restorations

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No new trials were available for this Cochrane review update. Only 8 RCTs were available providing inconsistent, low-quality evidence for a difference in postoperative hypersensitivity after placing a liner for posterior resin-based composite restorations in adult permanent teeth.

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Psychotherapy for adult depression: is it as good as it’s cracked up to be?

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Ellie Gant summarises a meta-analysis that asks: Was Eysenck right after all? A reassessment of the effects of psychotherapy for adult depression. The paper suggests that we seriously overestimate the benefits of psychotherapy by including biased trials in meta-analyses, and that there’s insufficient reliable research to be certain about the effectiveness of problem-solving therapy, interpersonal psychotherapy and behavioural activation.

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Can interventions help to improve social functioning in youth at risk of psychosis?

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Carla McEnery summarises a systematic review and meta-analysis of interventions and social functioning in youth at risk of psychosis.

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Fluoride toothpaste: Effects of different fluoride concentrations on caries

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This Cochrane review of effectiveness of different fluoride concentrations of toothpaste in reducing dental caries updates the 2010 review and includes 96 RCTs. It provideds good evidence to support the benefits of using fluoride toothpaste in preventing caries and demonstrates a does response effect.

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All-ceramic implant-supported single crowns

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This review of survival and technical complication rates of all-ceramic implant-supported single crowns included 41 mainly observational studies suggesting high survival rates for all-ceramic implant supported single crowns.

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Nonsurgical root canal therapy: What is the most effective oral premedication to reduce post treatment pain?

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This review of the most effective oral premedication in reducing pain in adults after nonsurgical root canal therapy including 16 studies. While a premedication of choice is suggested most outcomes are only supported by very low quality evidence.

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Irreversible pulpitis: What is the most effective local anaesthetic for inferior alveolar nerve block?

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This review of the most effective anaesthetic solutions for inferior alveolar nerve blocks for mandibular teeth with irreversible pulpitis included 11 RCTs. The findings suggest that mepivacaine with epinephrine performed better than lidocaine with epinephrine but the number of trials is limited and the quality of evidence was very low to moderate.

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Dental Implants: Number of implants and full-arch prosthesis survival

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19 studies (6 RCTs, 13 prospective studies) were included in this review assessing whether the number of dental implants per jaw has an influence on implant and/or prosthesis survival rate and complications with the findings suggesting no influence.

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