Sodium bicarbonate for the management of oral mucositis

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This review of the effectiveness of sodium bicarbonate in the prevention and management of oral mucositis included 11 RCTs. The included studies were small, hetrogeneous and suggested little benefit from the use of sodium bicoarbonate mouthwashes.

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Chlorine dioxide mouthwash for halitosis

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This review investigating the efficacy of chlorine dioxide mouthwashes in patients with halitosis included 10 RCTs. The findings suggest a potential benefit in the short-term. However the included studies are hetrogeneous and all have some concerns regarding bias so additional high quality well reported studies are needed.

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Oxycodone for acute dental pain?

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This review of the efficacy of oxycodone for post-operative acute dental pain included 13 studies. the findings showed that NSAIDs are generally superior for post-surgical dental pain, with a better adverse effect profile,so the need for oxycodone in dentistry is limited.

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Geographic tongue – global prevalence

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In this blog Rebecca Manson takes a look at a review assessing the global prevalence of geographic tongue. 14 studies were included suggesting a prevalence of 3% (95%CI 0.4% to 5.5%)

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Oral submucous fibrosis – malignant transformation rate

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In this blog we look at a review of the malignant transformation rate (MTR) for oral submucous fibrosis (OSF). The review included 16 studies estimating the malignant transformation rate as 6% (95%CI: 2% to 10%)

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Recurrent aphthous stomatitis – topical interventions

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This review of the efficacy and safety of topical interventions used for recurrent aphthous stomatitis included 72 studies assessing 29 different interventions. Most of the interventions did not demonstrate significant differences with limitednumbers of studies for some interventions and overal limitations in the quality of the evidence.

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Burning mouth syndrome treatments – network meta-analysis

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This review of all treatments for the relief of pain associated with burning mouth syndrome (BMS) as compared with no intervention or placebo included 44 RCTs. There was moderate certainty evidence that clonazepam is likely to reduce the pain of BMS compared with placebo.

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Antibiotics for dental infections – Short or long duration courses?

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing short (3–5 days) or longer courses (≥7 days) of antibiotics for the treatment of dental infections in general practice only included one small RCTs. No differences were seen between short an dlong courses but the findings should be interpreted cautiously becaise of the limited data available.

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Metronidazole for treatment of non-periodontal dental infections

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This review of whether metronidazole used as monotherapy or in addition to a β-lactam antibiotic offers any additional benefit over β-lactam monotherapy in non- periodontal dental infections includes 3 RCTs. The findings suggest that metronidazole does not provide superior clinical results compared to β-lactam antibiotics for the treatment of non-periodontal dental infections. However the evidence is limited and of low quality.

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