Additives to lidocaine and the success of the inferior alveolar nerve block

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This review of the effect of additives incorporated into lidocaine solution on the success of inferior alveolar nerve block (IANB) included 12 RCTs. The findings suggest that additives did not improve the success rate of IANB but the evidence is of low to very low certainty.

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Antibiotics to prevent bacterial endocarditis following dental procedures

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This Cochrane review update of antibiotic prophylaxis before invasive dental procedures in people at risk or at high risk of bacterial endocarditis included one case-controlled study. Consequently, there is no clear evidence about whether antibiotic prophylaxis is effective or ineffective against bacterial endocarditis in at-risk people who are about to undergo an invasive dental procedure.

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Ibuprofen prior to lower third molar removal

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This review of the effect of pre-emptive ibuprofen on post-operative pain after lower third molar surgery included 5 RCTs. Only one of the included studies was at low risk of bias so there is insufficient evidence to support the routine use of pre-emptive ibuprofen to reduce post-operative pain after lower third molar removal

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Management of dental patients taking anticoagulants or antiplatelet drugs

SDCEP- Anticoag-platelets 2022

We take a look at the recently updated guidance on the Management of Dental Patients Taking Anticoagulants or Antiplatelet Drug from the Scottish Dental Clinical effectiveness programme (SDCEP).

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Oral lichen planus and autoimmune disorders

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This review of the prevalence of autoimmune disorders in patients with oral lichen planus (OLP) and their magnitude of association included 153 studies. while links between autoimmune thyroid diseases and diabetes mellitus where shown a majority of the included studies were of low quality.

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Oral lichen planus and malignant transformation

Lichen_planus

This review of high quality studies of oral lichen planus malignant transformation rate included 10 observational studies. The findings found a higher level of malignant transformation in higher quality studies 2.28% (95%CI; 1.49 to 3.20) compared with reviews including lower quality studies 1.14% (0.84 to 1.49).

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Microwave disinfection of acrylic dentures

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This review of effect of microwave disinfection on the dimensional stability of denture base acrylic resins included 7 in-vitro studies. A wide range of microwave disinfection protocols were used with the reviewers specifying two protocols that may be safe. However because of the heterogeneity and the small number of studies included these finding should be considered cautiously.

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Osteonecrosis in bisphosphonate users having dental procedures

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This review of the the frequency of osteonecrosis of the jaw in bisphosphonate users undergoing dental interventions included 27 studies. having dental procedures of 2.7% (95%CI: 0.9 to 5.2%) being higher in those having dental extractions 4.1% (95%CI: 1.5 to 7.7%).

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Topical hyaluronic acid for recurrent aphthous stomatitis

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This review of the efficacy of topical hyaluronic acid (HA) for reducing the signs and symptoms of recurrent aphthous stomatitis (RAS) included 9 studies 8 of which were RCTs. The findings suggest that HA may be a potential treatment option for RAS but the evidence is of very low certainty.

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