COX-2 inhibitors for pain management after third molar removal

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing the efficacy of Cox-2 inhibitors with ibuprofen after third molar removal included 12 RCTs suggesting that COX-2 inhibotors and Ibuprofen provide similar pain relief at 6, 8, and 12 h after third molar removal.

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Geographic tongue and psoriasis

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This review assessing the prevalence of geographic tongue in psoriatic and non-psoriatic patients includded 11 cas-controlled studies. Meta-analysis showed that the odds of having geographic tongue in patients with psoriasis was higher OR = 3.53 (95%CI; 2.56-4.86).

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Sodium lauryl sulphate (SLS): Does SLS-free toothpaste use benefit patients with recurrent aphthous stomatitis

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This review of the effects of sodium lauryl sulphate (SLS) free and SLS-containing toothpastes in patients with recurrent aphthous stomatitis (RAS) included 4 small RCTs with the findings suggesting that patients with RAS may benefit from using SLS-free toothpaste. However the quality of teh availabel studies is very low.

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Oral mucosal disorders during pregnancy – How common are they?

Pregnant women taking antidepressants should be made of the benefits and risks of this treatment

This review of the prevalence of oral mucosal lesions during pregnancy included 15 observational studies from 9 countries. Gingival hyperplasia was most commonly report however the quality of the available evidence was assessed as very low.

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Dental visits and head and neck cancer

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This review of a link between past dental visits/check-ups and the incidence cancers of head and neck includes 38 studies the majority of which are case-controlled studies. The findings suggest that those are irregular of never attenders are more likely to have head and neck cancer.

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Aloe vera for treatment of oral submucous fibrosis?

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This review effectiveness of aloe vera on alleviating the symptoms of oral submucous fibrosis included 6 RCTs . The findings suggest a possible benefit but 5 of the trials were at high risk of bias so the findings should be viewed cautiously.

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Oral lichen planus and diabetes: are they associated?

Lichen_planusWickham's

This review of the relationship between oral lichen planus and diabetes included 22 studies. While both meta-analysis suggest a relationship the confidence intervals cross the line of no effect so are not statistically significant.

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Geographic tongue: little evidence for the management of symptomatic cases

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This review of treatments for the management of symptomatic benign migratory glossitis (BMG) only included 11 small low quality studies providing little evidence for the management of symptomatic BMG.

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Laser therapy for oral lichen planus

Lichen_planusWickham's

This review comparing low level laser therapy (LLLT) with steroids for the treatment of oral lichen planus only identified 5 studies none of which were at low risk of bias. Further high quality trials are needed to assess the efficacy of LLLT.

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