Topical anaesthesia: Does it reduce pain perception of local anaesthetic injections?

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This review of the effectiveness of topical anaesthesia in in reducing pain during local anaesthetic injections for dental procedures included 22 RCTs. Statistically significant differences were seen during needle puncture with topical anaesthetic use in the maxilla and palate but not the mandible.

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Denture stomatitis: Are natural products effective?

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This review comparing topical natural substances with conventional antifungals in the treatment of denture stomatitis included 17 studies 14 of which were RCTs. A wider range of natural products were tested and showed similar efficacy to antifungals however, almost all the studies were at high risk of bias so the certainty of the evidence is very low.

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Diagnostic accuracy of salvia tests for SARS-CoV-2

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This review of the use and diagnostic accuracy of saliva tests for the detection of SARS-CoV-2 included 16 studies. THe findings suggests good diagnostic accuracy but furteher research is needed to determine confounding factors such as method and time of sample collection, transport medium, storage etc. prior to population testing.

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Prevalence of burning mouth syndrome

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This review evaluating the worldwide prevalence and epidemiology profile of burning mouth syndrome included 18 studies. Population based studies suggest an overall prevalence of 1.73% and clinically-based studies a 7.72% prevalence.

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Oral leukoplakia and rate of malignant transformation

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This update of an earlier review of the malignant transformation rate of oral leukoplakia included 24 retrospective studies. The pooled proportion of malignant transformation was 9.8% (95%CI; 7.9 to 11.7%)

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Interventions for oral lichen planus

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This systematic review and network meta-analysis comparing interventions for the management of oral lichen planus included 55 RCTs. While the findings suggested that topical corticosteroids may be most effective the evidence is of low to very low certainty.

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COVID-19 Dental Elf Blogs – 5

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Since the emergence of the SARS-CoV-2 virus just over a year ago we have published a number of dental blogs relevant to COVID-19. The blogs cover topics such as dental teams’ generic risk of disease, baseline risk of covid-19, asymptomatic patients and the risk of community spread, digital thermometers, mouthwash use, surgical mask types, gown [read the full story…]

Recurrent aphthous stomatitis and serum zinc levels

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This review of the potential association between zinc levels and occurrence of Recurrent aphthous stomatitis (RAS) included 19 case-controlled studies. The findings show a sigificant association between low zinc levels and RAS.

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Oral manifestations of COVID-19

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This review of the oral signs and symptoms in patients with COVID-19 includes 40 studies (33 cross-sectional and 7 case reports). The findings show a significant association with taste disorders but little in relation to other oral disorders. As this is planned to be a living review it will be interesting to see if further evidence emerges.

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