Once symptoms stabilise after a first episode of psychosis, should medication continue? A four-year RCT explores the risks and rewards of dose reduction.
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DDD affects around 2% of people but has no approved treatment. A new feasibility trial asks whether CBT-f-DDD could change that.
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Large pragmatic trial found metformin plus lifestyle intervention reduced weight gain in young people with bipolar disorder taking antipsychotics. Effect significant but modest at 6 and 24 months.
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Oxytocin alone didn’t speed wound healing in couples, but combined with affectionate touch and partner appreciation, it showed modest benefits. Social context matters more than hormones.
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In this small RCT, vitamin C supplementation improved attention and work absorption in healthy young adults with low vitamin C levels, alongside changes in gut bacteria and inflammation markers.
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This innovative Australian trial suggests that different mental health app interventions worked better depending on students’ distress severity. One size doesn’t fit all, but which apps should students choose?
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This small trial suggests Psychological Wellbeing Practitioners might deliver focused panic therapy effectively. But with only 46 participants included in the final analysis, larger trials are needed to confirm.
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Feasibility trial found resistance training was safe and acceptable for people with psychosis in psychiatric rehabilitation wards, challenging assumptions about patient capabilities and safety.
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This study used Mendelian randomisation to test potential causal relationships between depression and 137 traits. Depression liability was linked to somatic diseases, inflammation, suicide risk, insomnia, lower cognitive function and functional impairments, though findings require validation.
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Although a flu vaccine activated the immune system and raised cytokine levels in this randomised trial, participants didn’t feel substantially different from the placebo group. Vaccine models can help study subtle inflammation effects.
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