Changing sleep patterns linked to cognitive decline and dementia

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Two large cohorts (one UK, one Chinese) found shifting from optimal to non-optimal sleep or stopping napping linked to higher dementia risk. But reverse causation limits certainty about prevention.

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Vitamin C, gut bacteria, and mental vitality: early findings

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In this small RCT, vitamin C supplementation improved attention and work absorption in healthy young adults with low vitamin C levels, alongside changes in gut bacteria and inflammation markers.

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Do antipsychotics slow down thinking? New evidence from healthy volunteers

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New research reveals how antipsychotic medications affect working memory speed in healthy adults, providing crucial insights into the cognitive side effects of these widely prescribed drugs.

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The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in ‘treatment-resistant depression’

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A big new study suggests that certain genetic traits—like insomnia risk and neuroticism—may make depression harder to treat, while protective traits include education and cognitive ability.

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What’s the matter? The role of white matter microstructure in depression-related cognitive decline

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Fionnuala Rogers discusses a study on the role of white matter microstructure in depression-related cognitive dysfunction, which highlights the importance of viewing major depressive disorder not only as a mood disorder, but as a condition with significant neurocognitive implications.

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Probiotics for bipolar disorder and schizophrenia

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Mary Butler explores a recent randomised controlled trial of probiotic formulations for patients with bipolar disorder or schizophrenia spectrum disorder.

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Cognition and heterogeneity in first-episode psychosis before antipsychotic treatment

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Ana Veic looks at an updated systematic review which suggests that patients with psychosis display cognitive difficulties very early in the disease process, and concludes this variation in cognitive function should prompt individual clinical assessments to optimise care.

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Antidepressants, cognition, and emotional blunting: what’s the evidence?

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Angharad de Cates reviews a recent Danish trial, which finds that escitalopram reduced participants’ reinforcement sensitivity compared to those on placebo. This lower reinforcement sensitivity may be similar to the emotional blunting effect often reported by patients during SSRI treatment.

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Social media use and disordered eating: Australian study finds a link in young teenagers

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Francesca Bentivegna reviews a recent Australian study which finds a significant association between social media use and disordered eating in young adolescents.

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