Sophie Fairweather explores a recent paper which suggests that the inflammatory cytokines IL-2 and IL-6 are associated with both the risk of developing depression, and with depression severity, although this relationship is modified by sex.
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Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.
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Yara Toenders and Lianne Schmaal consider the links between inflammatory dysregulation and depression in young people, by reviewing a recent study carried out by researchers in the US, and also by presenting the results of their own recent #ActiveIngredientsMH review, which was funded by the Wellcome Trust.
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This Cochrane review of cytokines and growth factors for preventing oral mucositis in patients having cancer treatment included 35 RCTs finding keratinocyte growth factor beneficial in the prevention of oral mucositis .
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This review included 17 studies and 843 patients. A wide range of cytokines/chemokines were assessed but the available evidence is not sufficient to prove that there are distinct differences between patients with aggressive periodontitis and those with chronic periodontitis.
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