Higher doses of antidepressants “not optimal”, according to new review

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Jonathon Tomlinson considers his options as a GP supporting people with depression and complex needs, after reading a new systematic review and dose-response meta-analysis, which suggests that higher doses of antidepressants bring maximum side effects with only marginal gains.

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Antidepressant withdrawal: slower and lower tapering of SSRIs

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A group of UCL Masters Students summarise a recent personal view by Mark Horowitz and David Taylor about tapering of SSRI treatment to mitigate antidepressant withdrawal symptoms.

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Daily skunk cannabis use associated with a 5-fold increase in psychosis risk

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Luke Sheridan-Reins explores a recent paper on the contribution of cannabis use to variation in the incidence of psychotic disorder across Europe.

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Improving care for people with bipolar disorder: meeting unmet needs

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Leela Sathyaputri and Jess Fiedorowicz write their debut elf blog on a narrative review of the recent bipolar disorder literature entitled: “Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives”.

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Compulsory detention under the Mental Health Act: significantly more likely if you come from a BAME or migrant group

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Ian Cummins explores a recent international systematic review and meta-analysis, which highlights ethnic variations in compulsory detention under the Mental Health Act.

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Smoking cessation for people with severe mental illness? “Oh yes they can!” SCIMITAR+

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David Shiers and Peter Byrne summarise the new SCIMITAR+ trial out today in The Lancet Psychiatry, which evaluates a bespoke smoking cessation intervention for people with severe mental illness.

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Community supported discharge service for teenagers leaving psychiatric hospital

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Robyn Murphy summarises an RCT that compares the effectiveness and cost-effectiveness of an intensive community supported discharge service versus treatment as usual for adolescents with psychiatric emergencies.

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Hope for recovery: REFOCUS-PULSAR recovery training in specialist mental health care

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Simon Bradstreet welcomes the positive findings of the REFOCUS-PULSAR trial, which evaluated recovery-oriented practice training in specialist mental health care.

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Compulsory Community Treatment does not reduce readmissions or length of stay in hospital

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John Baker explores a systematic review of compulsory community treatment to reduce readmission to hospital and increase engagement with community care in people with mental illness.

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Medication for ADHD: what works for adults, adolescents and children

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Dean Connolly is impressed by a recent systematic review and network meta-analysis, which compares the efficacy and tolerability of medication for ADHD in children, young people and adults.

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