This study used Mendelian randomisation to test potential causal relationships between depression and 137 traits. Depression liability was linked to somatic diseases, inflammation, suicide risk, insomnia, lower cognitive function and functional impairments, though findings require validation.
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How often do people with eating disorders switch diagnoses, recover, or relapse? This large Danish study follows more than 10,000 people over nearly a decade, uncovering patterns of remission and genetic vulnerability that could help shape more personalised care.
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Psychiatric hospitalisation can save lives, but it also carries major personal and economic costs. Could early warning scores help predict who’s most at risk, allowing for earlier, more targeted support? This new BMJ Mental Health study by Taquet and colleagues explores the potential.
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Dr Laura Naysmith summarises important new research on the mental health impacts of premature menopause.
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Laura Naysmith summarises a study of menopausal hormone therapy (also known as HRT), which suggests the treatment is linked with reduce the risk of psychosis relapse in menopausal women.
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Shuichi Suetani blogs a new study published today in The Lancet Psychiatry, which suggests that those patients who might benefit most from evidence-based guidance are the least represented in clinical trials about ADHD medication. Is it time to reconsider the value we place on RCTs when they do not include the vast majority of people who need help?
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Amelia Mullett summarises an Australian RCT on the efficacy of a short message service brief contact intervention (SMS-SOS) in reducing repetition of hospital-treated self-harm.
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Florian Walter summarises a retrospective cohort study published in The Lancet Psychiatry that investigates whether early trajectories of clinical global impression severity can transdiagnostically predict later psychiatric hospitalisation.
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Kris Deering considers a 2-year prospective observational study published in the Lancet Psychiatry which found strong links between stressful life events and relapse in first-episode psychosis.
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Ian Hamilton reviews a new controlled interrupted time series study published in The Lancet evaluating the impact of alcohol minimum unit pricing on deaths and hospitalisations in Scotland.
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