In his debut blog, Franco De Crescenzo summarises a narrative review that finds good evidence for the short-term pharmacological treatment of ADHD.
[read the full story...]ADHD: which medications are most effective and safe?
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The benefits and harms of antidepressants for youth depression and anxiety #ActiveIngredientsMH
Mark Horowitz and Joanna Moncrieff consider a new #ActiveIngredientsMH review published today in The Lancet Psychiatry, which looks at the knowns and unknowns of antidepressant treatment in young people with depression and anxiety: efficacy, predictors, and mechanisms of action.
[read the full story...]Expertise from outside the Academy: tapering off antidepressants
Mark Horowitz considers a recent article written by Adele Framer, Founder of SurvivingAntidepressants.org, which describes how best to help people who are tapering off antidepressants.
[read the full story...]Antipsychotics for schizophrenia: do they provide a longer, healthier life?
Paul Heron from the Closing the Gap Network writes his debut blog about a 20‐year cohort study of physical morbidity and mortality in relationship to antipsychotic treatment in a huge group of people with schizophrenia in Finland.
[read the full story...]Antipsychotics and metabolic function in people with schizophrenia
Peter Haddad and Sami Ouanes review a network meta-analysis of the impact of antipsychotic drugs on metabolic function in people with schizophrenia.
[read the full story...]Are antidepressants safe? A new umbrella review of observational studies suggests they are, but we need more accurate data
Andrea Cipriani and Anneka Tomlinson scrutinise a brand new umbrella review of the associations between antidepressants and adverse health outcomes, which suggests that antidepressants are safe for most people who experience mental health difficulties.
[read the full story...]In adults with major depression, antidepressants may increase the risk of suicide
Douglas Badenoch explores a meta-analysis of follow-up data from clinical trials of antidepressants, which found a small but significant increase in suicide risk.
[read the full story...]Higher doses of antidepressants “not optimal”, according to new review
Jonathon Tomlinson considers his options as a GP supporting people with depression and complex needs, after reading a new systematic review and dose-response meta-analysis, which suggests that higher doses of antidepressants bring maximum side effects with only marginal gains.
[read the full story...]Antidepressants and weight gain: long-term population impact #SUSANAsurvey
Andrea Cipriani and Anneka Tomlinson summarise a 10-year cohort study of antidepressant use and incidence of weight gain.
They also launch their new SUSANA project: Survey for Understanding Side effects of ANtidepressants in Adults. Please take the SUSANA survey now!
[read the full story...]Antidepressant withdrawal: slower and lower tapering of SSRIs
A group of UCL Masters Students summarise a recent personal view by Mark Horowitz and David Taylor about tapering of SSRI treatment to mitigate antidepressant withdrawal symptoms.
[read the full story...]