Pregnancy and bipolar disorder: international prescribing consensus?

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Dean Connolly looks at an international study which asks: Is there consensus across evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?

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Dropping out of virtual reality exposure therapy for anxiety: comparison with in-vivo exposure therapy

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Aislinn Bergin writes her debut elf blog on a recent meta-analytic examination of attrition in virtual reality exposure therapy for anxiety disorders.

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Mandibular advancement devices in obstructive sleep apnoea: side effects

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21 studies mainly retrospective studies were included in this review of the dental and skeletal effects of mandibular advancement devices in treatment of obstructive sleep apnoea. while the findings suggest a number of potential side effects the quality of the available evidence in low.

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Antidepressant withdrawal: reviewing the paper behind the headlines

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Joseph Hayes and Sameer Jauhar set the record straight on antidepressant withdrawal. They show how the recent review by Davies and Read is seriously flawed and does not accurately portray the data. They conclude that we urgently need clearer evidence on the incidence, severity and duration of any symptoms related to antidepressant withdrawal.

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Adverse effects of psychotherapy for depression: new meta-analysis looks at deterioration rates

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Edel Mc Glanaghy reacquaints us with the negative effects of psychotherapies for adult depression, through an impressive new meta-analysis of trials that measure deterioration rates in patients receiving psychotherapy compared with controls.

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Low dose Amisulpride for very late onset schizophrenia-like psychosis: the ATLAS study

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Elwira Lubos summarises the recent ATLAS RCT of antipsychotic treatment for very late-onset schizophrenia-like psychosis, which provides evidence for the effectiveness of a very low dose of Amisulpride (100 mg).

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Sexual function matters to people living with serious mental illness

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Rudiger Pittrof and Elana Covshoff from SHRINE (Sexual and Reproductive Health Rights, Inclusion and Empowerment) explore a recent review, which looks at the impact of severe mental disorders and psychotropic medications on sexual health and its implications for clinical management.

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People with severe mental illness have more adverse outcomes from medical or surgical treatment

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Laoise Renwick considers the findings of a recent systematic review on the safety of service users with severe mental illness receiving inpatient care on medical and surgical wards.

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Antipsychotic effectiveness: the numbers don’t lie, check the scoreboard

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Students and Teachers from the King’s College London PNoMH Distance Learning MSc summarise a major new meta-analysis that brings together the last 60 years of placebo-controlled antipsychotic drug trials in acute schizophrenia.

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SSRIs and suicidality: effects of SSRIs on rating-scale-assessed suicidality in adults with depression

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Rina Dutta and Patrick McLaughlin summarise a new study looking at the effects of SSRIs (Selective Serotonin Reuptake Inhibitors) on rating-scale-assessed suicidality in adults with depression.

This study published in the British Journal of Psychiatry supports the conclusion that SSRIs remain a safe and effective treatment in depression for those aged 18 and over.

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