Large pragmatic trial found metformin plus lifestyle intervention reduced weight gain in young people with bipolar disorder taking antipsychotics. Effect significant but modest at 6 and 24 months.
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Guidelines say metformin can help prevent weight gain from antipsychotics like olanzapine, but this large UK study shows it’s rarely prescribed. What’s stopping us?
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This review of metformin as an adjunct to scaling and root planing for chronic periodontitis included 5 RCTs that were of limited quality and mainly from one research group. The findings suggest benefit.
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Individuals with severe mental illness (SMI) have shortened life expectancies compared to the general population. This is partly down to higher rates of chronic physical illness. Cardiovascular disease (CVD) is the leading cause of death among patients using mental health services. It is assumed that interventions used to reduce CVD are similarly effective in patients with [read the full story…]
The use of case studies to illustrate learning and to improve clinical practice is an established method. This case study of a woman with learning disabilities presenting with polycystic ovary syndrome is presented by the authors to explore mental health symptoms associated with the condition. Polycystic ovary syndrome is a condition that affects the ovaries [read the full story…]
