Can we predict and prevent weight gain in early psychosis?

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New research suggests that weight gained in the first 12 weeks of antipsychotic treatment is the biggest driver of long-term obesity in psychosis.

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Is depression a cause or consequence? Using genetics to untangle causal relationships

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This study used Mendelian randomisation to test potential causal relationships between depression and 137 traits. Depression liability was linked to somatic diseases, inflammation, suicide risk, insomnia, lower cognitive function and functional impairments, though findings require validation.

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A new way of looking for mental health risk factors: the PsyRiskMR database

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PsyRiskMR is a new database that helps researchers investigate risk factors for common psychiatric disorders using Mendelian randomization.

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Is vaping really a gateway to smoking? New review of youth vaping confirms uncertainty

Clinicians who withhold opiates to protect patients from self-harm may be doing more harm than good; is it time to retire this outdated assumption?

Vaping is helping millions quit smoking, but concerns about teen uptake remain. A new blog explores whether the ‘gateway hypothesis’ stands up to scrutiny in the latest umbrella review of vaping harms in young people.

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The genetic relationship between ADHD and depression

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Tim van der Es discusses a recent paper that investigates whether ADHD causally increases the risk of subsequent major depression diagnoses. The study findings underscore the need for effective treatment and assessment of ADHD and a requirement for a deeper understanding of the potential causal mechanisms linking ADHD and depression.

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