A large Australian study suggests that atypical depression is genetically, metabolically and clinically distinct, with poorer response to SSRIs and SNRIs.
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New research suggests that weight gained in the first 12 weeks of antipsychotic treatment is the biggest driver of long-term obesity in psychosis.
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Large pragmatic trial found metformin plus lifestyle intervention reduced weight gain in young people with bipolar disorder taking antipsychotics. Effect significant but modest at 6 and 24 months.
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A 15-year analysis of UK primary care records showed steep and sustained weight gain after an SMI diagnosis, especially among younger adults and people prescribed antipsychotic medication. Yet very few received referrals for weight-management support, raising important questions about practice and policy.
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Guidelines say metformin can help prevent weight gain from antipsychotics like olanzapine, but this large UK study shows it’s rarely prescribed. What’s stopping us?
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Caroline Touzeau and Caitlin Lloyd blog about a recent longitudinal cohort study that investigated patterns of maladaptive exercise in young people, which supports “re-framing motivations for exercise in youth away from weight loss at a population level”.
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In her debut blog, Eline van Bree summarises a recent pre-post observational cohort study, which explores the effectiveness of delivering evidence-based eating disorder treatment via telemedicine for children and young people.
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In her debut blog, Sarah Nicholson summarises a systematic review of pre-pregnancy BMI and the risk of antenatal and postnatal depression.
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Meenakshi Shukla summarises a systematic review exploring the trajectory of blood pressure, body mass index, cholesterol and incident dementia.
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Peter Haddad and Sami Ouanes review a network meta-analysis of the impact of antipsychotic drugs on metabolic function in people with schizophrenia.
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