Stop, reduce or stay on antipsychotics after first-episode psychosis?

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Once symptoms stabilise after a first episode of psychosis, should medication continue? A four-year RCT explores the risks and rewards of dose reduction.

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Involuntary psychiatric patients face prolonged suicide risk post-discharge

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Suicide risk following involuntary psychiatric care remains elevated for years, with highest risk in the first month. Personality disorder patients face greatest long-term vulnerability.

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Prescribing in borderline personality disorder: Evidence, relationships, and the realities of practice

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No drugs are officially approved for borderline personality disorder, yet prescribing is widespread. This systematic review explores why clinicians prescribe, the pressures they face, and what it means for patient care.

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Pragmatic prescribing: why GPs offer beta-blockers for anxiety, despite guideline gaps

GPs’ perceived benefits of beta-blockers for anxiety underscore a need for further research and updated clinical guidance to align practice with evidence.

Beta-blockers like propranolol are being prescribed more often for anxiety in UK primary care, even though they don’t appear in national guidelines. This new qualitative study explores why GPs turn to them, and what that says about evidence, safety, and patient choice.

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Are current perinatal depression screening practices following guidelines’ recommendations?

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Angelica Tong summarises a recent Chinese review of perinatal depression screening and international guideline recommendations, which finds that routine screening and referrals for perinatal depression were not widely adopted in clinical practice.

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A review of guidelines for perinatal mental health: psychological and psychosocial assessment and intervention

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Lucy Purnell summarises a systematic review of clinical psychological guidance for perinatal mental health from the UK, Australia and Canada.

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When we help people with PTSD who are suicidal, do we give them the care they need?

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A group of MSc students at UCL summarise a study exploring the secondary mental health care treatment patients with comorbid PTSD and suicidality receive in London.

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Antidepressant withdrawal or depression relapse? International guidelines on antidepressant discontinuation are unclear

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Adele Framer summarises a systematic review which finds that major guidelines on antidepressant discontinuation only give clinicians vague guidance on distinguishing withdrawal from relapse.

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Treating PTSD in adults: EMDR and trauma-focused CBT still lead the way

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Nada Abou Seif summarises a network meta-analysis which finds that EMDR and trauma-focused CBT remain the most effective ways to treat adult PTSD.

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Stratified care versus stepped care for depression: which is more effective?

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Sarah Watts reviews a cluster randomised clinical trial investigating the effectiveness of stratified care compared to stepped care for depression, which has implications for IAPT services.

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