Murtada Alsaif considers a systematic review and meta-analysis published in the Lancet Psychiatry exploring the response of different subgroups of patients with schizophrenia to different antipsychotic drugs.[read the full story...]
Can brain scans tell us how successful CBT for anxiety will be? Meta-analysis of task-based fMRI studies shows promise
Millie Lowther, Isabel Luetkenherm, Carlos Mena and Alexandra Pike summarise a recent fMRI meta-analysis, which finds that activation in brain circuits related to salience, interoception and emotional processing were found to predict a positive response to CBT in anxiety disorders.[read the full story...]
Youth anxiety and depression treatment not as good as we think? What should we tell the children?
Ola Demkowicz writes her debut elf blog about a study that evaluates reliable improvement rates in depression and anxiety at the end of treatment in adolescents.[read the full story...]
Improving antidepressant outcomes: what works for whom and why?
Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.[read the full story...]
Understanding the genetics of antipsychotic treatment response
Marcus Munafo looks at a Chinese genome-wide association study that claims to have identified some of the genes associated with response to antipsychotic treatment.[read the full story...]
Can early improvement be used to predict later response to antipsychotics in schizophrenia?
Tracey Roberts summarises a recent diagnostic test review, which suggests that early improvement can act as a predictor of later response to antipsychotics in schizophrenia.[read the full story...]
Biological markers for treatment response in first episode psychosis
Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress.[read the full story...]