Improving antidepressant outcomes: what works for whom and why?

rawpixel-792222-unsplash

Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.

[read the full story...]

Understanding the genetics of antipsychotic treatment response

simone-van-der-koelen-611419-unsplash

Marcus Munafo looks at a Chinese genome-wide association study that claims to have identified some of the genes associated with response to antipsychotic treatment.

[read the full story...]

Can early improvement be used to predict later response to antipsychotics in schizophrenia?

The increased risk of mood and anxiety problems found in people taking varenicline with pre-existing mental health conditions, needs to be investigated further.

Tracey Roberts summarises a recent diagnostic test review, which suggests that early improvement can act as a predictor of later response to antipsychotics in schizophrenia.

[read the full story...]

Biological markers for treatment response in first episode psychosis

shutterstock_96270467

Stephen Wood summarises a systematic review of biological markers for treatment response in first episode psychosis, which discusses a number of hot topics in this field including inflammation, infectious disease and oxidative stress.

[read the full story...]