Autism and social anxiety: qualitative research shows how we can help

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Rachel Symons summarises a qualitative study that explores the relationship between autism and social anxiety in male adults.

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Antidepressants and psychotherapy for adolescent depression: can they be compared? #ActiveIngredientsMH

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Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.

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Experience of psychotropic medication and decision-making

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Jennifer Rose Oulton reviews a qualitative study that explores the experiences of psychotropic medication use and decision-making for adults with learning disabilities and their carers.

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Botulinum toxin and idiopathic dentoalveolar pain

Botulinum toxin

This review of the use of botulinum toxin (BONT-A) for pain-relief in patients with persistent idiopathic dentoalveolar pain included just 3 small uncontrolled studies providing a very limited amounh of very low quality evidence.

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Stopping antidepressants: patient perspectives on barriers and facilitators

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Timothy Nyugen and Dafni Katsampa summarise a qualitative review of patient perspectives on the barriers and facilitators to stopping antidepressants.

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Mindfulness to support antidepressant withdrawal: patient views and experiences

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Hannah Bowers writes her debut blog on a recent qualitative study, which explores how mindfulness-based cognitive therapy can help people stop taking antidepressants and recover from depression. This paper includes the views and perspectives of participants in the 2015 PREVENT trial.

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Cost-effectiveness of CBT for depression: uncertainty remains

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Chris Sampson reviews a recent US study which looks at the cost-effectiveness of CBT versus second-generation antidepressants for the initial treatment of major depressive disorder.

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Are antidepressants safe? A new umbrella review of observational studies suggests they are, but we need more accurate data

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Andrea Cipriani and Anneka Tomlinson scrutinise a brand new umbrella review of the associations between antidepressants and adverse health outcomes, which suggests that antidepressants are safe for most people who experience mental health difficulties.

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In adults with major depression, antidepressants may increase the risk of suicide

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Douglas Badenoch explores a meta-analysis of follow-up data from clinical trials of antidepressants, which found a small but significant increase in suicide risk.

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Intranasal esketamine for treatment-resistant depression: the first clinical study

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Jodi Rintelman writes her debut elf blog on the first randomised controlled trial on the efficacy and safety of intranasal esketamine as an adjunctive treatment to antidepressants for treatment-resistant depression.

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