Antidepressants and weight gain: long-term population impact #SUSANAsurvey

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Andrea Cipriani and Anneka Tomlinson summarise a 10-year cohort study of antidepressant use and incidence of weight gain.

They also launch their new SUSANA project: Survey for Understanding Side effects of ANtidepressants in Adults. Please take the SUSANA survey now!

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Antidepressant withdrawal: slower and lower tapering of SSRIs

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A group of UCL Masters Students summarise a recent personal view by Mark Horowitz and David Taylor about tapering of SSRI treatment to mitigate antidepressant withdrawal symptoms.

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Genetics of depression: understanding risk and improving treatment

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Douglas Levinson on a genome-wide meta-analysis of depression in 807,553 individuals, which identifies 102 independent variants relating to the genetics of depression.

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Improving antidepressant outcomes: what works for whom and why?

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Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers including both genetic and neuroimaging data.

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Antidepressant withdrawal: reviewing the paper behind the headlines

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Joseph Hayes and Sameer Jauhar set the record straight on antidepressant withdrawal. They show how the recent review by Davies and Read is seriously flawed and does not accurately portray the data. They conclude that we urgently need clearer evidence on the incidence, severity and duration of any symptoms related to antidepressant withdrawal.

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Preventive cognitive therapy when continuing or tapering off antidepressants

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Linda Gask is encouraged by the findings of a new high quality RCT (the DRD study), which compares preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in the prevention of depressive relapse or recurrence.

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“Where I End And You Begin”: A personal commentary on Russo’s ‘Through the eyes of the observed’ #PsychDrugDebate

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Sarah Carr shares her own experiences of psychiatric medication and provides a critical reading of Jasna Russo’s new #PsychDrugDebate paper: ‘Through the eyes of the observed: re-directing the research on psychiatric drugs’.

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How should we redirect research on psychiatric drugs? #PsychDrugDebate

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Alison Faulkner dissects the new McPin Foundation Talking Point Paper by Jasna Russo entitled: Through the eyes of the observed: re-directing research on psychiatric drugs.

Follow #PsychDrugDebate today on Twitter for further discussion about this vital issue.

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Polypharmacy for major depression: is practice evidence-based?

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Jessica Bone reports on a recent cross-sectional study that looks at the clinical correlates of augmentation/combination treatment strategies in major depressive disorder.

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Non-medical use of prescription drugs #NonMedicalDrugs

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Ian Hamilton and Julia Buxton from the University of York preview the #NonMedicalDrugs event that will take place in York on Friday 16th March 2018.

The meeting will bring together people who can offer personal and professional insights of the extent of the issue and how we can support people who develop problems.

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